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The 2024 Lasker–DeBakey Clinical Medical Research Award has been presented for the discovery of GLP-1 and its application to the treatment of obesity. Lasker winner Svetlana Mojsov, PhD, discusses her role in this innovative discovery and more with JAMA Senior Editor Anne Rentoumis Cappola, MD, ScM. Related Content: Chemistry Matters—From a Putative Peptide to Effective Treatments for Diabetes and Obesity https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.17571?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public Discovery of cGAS as a DNA-Sensing Enzyme That Triggers Inflammation https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.17873?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public GLP-1 for Treating Obesity—Origin, History, and Evolution https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.18000?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public AIDS in Africa—Impact of Research https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.18271?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public Podcast was originally published on September 19, 2024. https://edhub.ama-assn.org/jn-learning/audio-player/10.1001/jama.2024.18624?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public --------------------------------------------------------------------------------- Follow JAMA Author Interviews on: Youtube: https://www.youtube.com/playlist?list=PL4VOPuLXRs1dWJCIIu2iOIOWRGUc0nTOU Apple Podcasts: https://podcasts.apple.com/us/podcast/jama-author-interviews-covering/id410339697 Spotify: https://open.spotify.com/show/61HE3v2dmxyg3nsIRAK25C?si=bcbb384405d44b71 Pocket Casts: https://pca.st/DAh2 Your podcast app of choice: https://pod.link/410339697 Website: https://jamanetwork.com/journals/jama/pages/jama-author-interviews --------------------------------------------------------------------------------- For more from JAMA • https://www.jama.com • https://www.facebook.com/JAMAJournal • https://www.twitter.com/JAMA_Current • https://www.linkedin.com/company/jamanetwork Follow the JAMA Network • https://www.jamanetwork.com • http://www.jamanetworkaudio.com • https://www.facebook.com/JAMANetwork • https://www.twitter.com/JAMANetwork • https://www.instagram.com/JAMANetwork • https://www.pinterest.com/JAMANetwork

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In this video, we discuss ozempic weight loss. We also discuss ozempic weight loss before and after, and ozempic injection and how to use it. We also look at ozempic side effects, the "ozempic face" and ozempic for weight loss without diabetes. This video aims to answer questions like how ozempic works? how ozempic helps with weight loss? how does the ozempic pen work? and how ozempic injection works? Ozempic is a brand-name medication of the prescription drug Semaglutide. It helps people with type 2 diabetes by regulating hormones such as insulin, glucagon, and Glucagon-like peptide one (or GLP). It gained popularity in 2022, thanks in part to celebrities who used it or its variant Wegovy to slim down. People shared ozempic weight loss before and after stories. Ozempic weight loss is not without its controversies. It became so popular, that the intended group it was made for (type 2 diabetes) had a hard time getting it. It's 2023, and people are still seeking it out. And a new drug, Mounjaro, is on right Ozempic's trail, hoping to be a direct competitor with Ozempic. (about this video: ozempic, ozempic weight loss before and after, ozempic injection how to use, ozempic weight loss, ozempic commercial, ozempic face, ozempic side effects, ozempic weight loss stories, ozempic before and after, ozempic face before and after, ozempic injection, ozempic how to use, ozempic 1 mg, ozempic for weight loss without diabetes, how ozempic works, how ozempic helps with weight loss, how ozempic pen works, how ozempic can make you look older, how ozempic weight loss, how ozempic works vox, how ozempic works for weight loss, how ozempic injection works, how ozempic works animation, how ozempic is taken, ozempic how to take, ozempic how to get) #weightloss #bodytransformation #weightlosstips #weightlossjourney #health #healthtips #healthylifestyle #ozempicweightloss #ozempic

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Semaglutide is a medication that has been gaining popularity in recent years for its effectiveness in weight loss. Originally developed as a treatment for type 2 diabetes, semaglutide has shown promising results in helping individuals shed excess pounds. With the recent approval of a long-acting weekly dosage for weight loss, many are curious about the possibility of taking semaglutide every other week. In this article, we will explore expert opinions and guidelines on the use of semaglutide for weight loss and whether it can be taken biweekly.

Benefits of Semaglutide for Weight Loss

Semaglutide works by mimicking the effects of a hormone called GLP-1, which helps regulate blood sugar levels and appetite. By activating the GLP-1 receptors in the brain, semaglutide can reduce hunger and promote feelings of fullness, leading to a decrease in calorie intake and ultimately weight loss. Studies have shown that semaglutide can help individuals lose significant amounts of weight when combined with diet and exercise.

One of the key benefits of semaglutide is its ability to target the reward centers in the brain that are responsible for cravings and food intake. By dampening these signals, semaglutide can help individuals make healthier food choices and resist the temptation to overeat. Additionally, semaglutide has been shown to improve insulin sensitivity and reduce inflammation, which are both important factors in weight management.

Another advantage of semaglutide is its convenience and ease of use. With the recent approval of a weekly injectable dosage for weight loss, individuals can easily incorporate semaglutide into their routine without having to remember to take multiple doses throughout the day. This once-weekly injection has been shown to be safe and effective for long-term weight loss maintenance.

Potential Risks and Side Effects

While semaglutide can be an effective tool for weight loss, it is important to consider the potential risks and side effects associated with its use. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and tend to improve over time as the body adjusts to the medication.

More serious side effects of semaglutide may include pancreatitis, kidney problems, and thyroid tumors. It is important to discuss any concerns or pre-existing conditions with your healthcare provider before starting semaglutide for weight loss. Additionally, individuals with a history of eating disorders or mental health conditions should use caution when using semaglutide, as it may affect their relationship with food and body image.

There have been some reports of an increased risk of gallbladder-related events in individuals taking semaglutide. It is recommended that individuals with a history of gallbladder problems or gallstones discuss the potential risks and benefits of semaglutide with their healthcare provider before starting treatment.

Expert Opinions and Guidelines

Experts in the field of obesity medicine generally recommend using semaglutide for weight loss in combination with a comprehensive lifestyle intervention that includes diet, exercise, and behavior modification. While semaglutide can help individuals achieve significant weight loss, it is not a magic bullet and should be used as part of a holistic approach to health and wellness.

Some experts believe that taking semaglutide every other week may not be as effective as the once-weekly dosage for weight loss. The continuous activation of GLP-1 receptors provided by the weekly injection may be more beneficial in suppressing appetite and promoting weight loss compared to a biweekly dosing schedule.

Ultimately, the decision to take semaglutide every other week for weight loss should be made in consultation with a healthcare provider. Your provider can assess your individual needs and goals and recommend the most appropriate dosing schedule based on your medical history and lifestyle factors.

Conclusion

In conclusion, semaglutide can be a valuable tool for weight loss when used in combination with a healthy diet and regular exercise. While taking semaglutide every other week may be an option for some individuals, experts generally recommend the once-weekly dosage for optimal results. It is important to weigh the potential benefits and risks of semaglutide with your healthcare provider before starting treatment. By following expert guidelines and recommendations, you can achieve long-lasting weight loss success with semaglutide.

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