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Send us a text (https://www.buzzsprout.com/twilio/text_messages/2193439/open_sms) Why aren't GLP-1 medications working for everyone? You may be frustrated that semaglutide or tirzepatide isn't helping you lose weight like it has for others. The problem might not be your diet or willpower - it could be genetic. Discover how a single gene called TCF7L2 may be sabotaging your weight loss efforts with GLP-1 medications, and what you can do about it. BY THE TIME YOU FINISH LISTENING, YOU'LL DISCOVER: • Why 10-15% of people may be "non-responders" to GLP-1 agonists for weight loss • The gene that could impact the effectiveness of  GLP-1  • Strategies to overcome genetic resistance to GLP-1 medications This episode could be a game-changer if you've been struggling with weight loss despite using GLP-1 agonists. RESEARCH ARTICLES: 1. Efficacy And Safety Of Semaglutide For Weight Loss In Adults With Overweight Or Obesity (https://pubmed.ncbi.nlm.nih.gov/36188627/) 2. A review of receptor interactions and co-stimulation, Peptides (https://www.sciencedirect.com/science/article/pii/S0196978122000158?via%3Dihub) 3. Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms (https://link.springer.com/article/10.1007/s00125-007-0753-6) Support the show (https://www.buzzsprout.com/2193439/support) WANT MORE? Let's get your health goals in order in a 15 minute Revive and Thrive Session (https://p.bttr.to/3GbUGT4) . Learn How to Safely Use Weight Loss Medications in our Empowerment Hour (https://lyfebalance.ac-page.com/weight-loss-meds-webinar) . Get a jumpstart on your health with our 10-Day Elite Health Reset (https://bit.ly/elitehealthreset) . What could your Genetic Blueprint reveal? Get a sample nutrigenomics report. (https://lyfebalance.activehosted.com/f/168) Be part of our Community: Join us on Facebook (https://www.facebook.com/groups/550360067419576/) PRACTITIONERS Interested in learning how you can help patients focus more on nutrition? Schedule a call here. (https://l.bttr.to/md0fc) FOLLOW US Instagram/LinkedIn/Tiktok: @drtamarlawful (https://www.instagram.com/drtamarlawful/) Liked this episode? Share it with a friend. Love the show? Write a 5-star Apple review (https://podcasts.apple.com/us/podcast/pivoting-pharmacy-with-nutrigenomics/id1709061093) . No Apple? Leave your review here (https://ratethispodcast.com/pivotingpharmacy) .

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In this video, I’ll break down some of the top publicly traded companies involved in developing GLP-1 receptor agonists, the class of drugs making waves in weight loss and diabetes treatments. These medications, including Ozempic and Mounjaro, are becoming incredibly popular. Let’s dive into the companies behind them and what they’re working on. Novo Nordisk (NVO): The creator of Ozempic and Wegovy, two of the most well-known GLP-1 drugs for managing diabetes and obesity. Eli Lilly (LLY): The company behind Mounjaro, another injectable GLP-1 drug that’s shown significant weight loss effects. Pfizer (PFE): Researching oral GLP-1 receptor agonists, a potential game-changer in this space. Amgen (AMGN): Developing new injectable treatments for obesity, with a focus on GLP-1 therapies. Altimmune (ALT): Working on Pemvidutide, a GLP-1/glucagon dual receptor agonist for obesity. Viking Therapeutics (VKTX): Developing VK2735, a GLP-1/glucagon receptor agonist aimed at weight loss and metabolic disorders. Structure Therapeutics (GPCR): Creating oral GLP-1 receptor agonists for obesity and diabetes. Watch the full video to get insights into these stocks and what they could mean for the future of weight loss treatments!

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