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Last updated on 2025-11-18

2025-11-18

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Recently, there has been a lot of buzz surrounding the use of Semaglutide for weight loss. As one of the newest drugs on the market, many people are curious about its effectiveness and whether or not it is FDA-approved for weight loss. In this article, we will delve into the details of Semaglutide, its approval status by the FDA, and what guidelines are in place for its use in weight loss management.

What is Semaglutide?

Semaglutide is a medication that belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. It is typically used to improve blood sugar control in adults with type 2 diabetes. However, in recent years, studies have shown that Semaglutide may also be effective in promoting weight loss.

Semaglutide works by mimicking the effects of natural hormones in the body that help to regulate blood sugar levels and appetite. By increasing feelings of fullness and reducing cravings, Semaglutide can lead to decreased food intake and ultimately, weight loss.

It is important to note that Semaglutide is not a magic pill for weight loss. It is intended to be used in conjunction with a healthy diet and regular exercise for maximum effectiveness. Additionally, like any medication, Semaglutide may come with potential side effects and risks that should be discussed with a healthcare provider.

FDA Approval for Weight Loss

As of now, Semaglutide is not FDA-approved specifically for weight loss. However, the drug has been approved for the treatment of type 2 diabetes at higher doses. It is these higher doses of Semaglutide that have shown promising results in clinical trials for weight management.

In fact, a study published in the New England Journal of Medicine found that individuals who took a higher dose of Semaglutide lost significantly more weight compared to those who took a placebo. These findings have sparked interest in using Semaglutide off-label for weight loss purposes.

While healthcare providers can legally prescribe medications off-label for conditions other than what they were initially approved for, patients should be aware of the potential risks and benefits. It is always recommended to consult with a healthcare provider before starting any new medication, including Semaglutide for weight loss.

Guidelines for Semaglutide Use

For individuals considering Semaglutide for weight loss, there are certain guidelines that should be followed to ensure safe and effective use of the medication. Firstly, Semaglutide should only be used under the guidance of a healthcare provider who can monitor progress and adjust the dosage as needed.

It is also important to understand that Semaglutide is not a one-size-fits-all solution for weight loss. Factors such as age, weight, medical history, and lifestyle habits can all impact the effectiveness of the medication. A healthcare provider can help determine if Semaglutide is the right choice for an individual based on these factors.

Furthermore, individuals should be aware of the potential side effects of Semaglutide, which can include nausea, vomiting, diarrhea, and constipation. These side effects are typically mild and may subside over time but should be reported to a healthcare provider if they persist or worsen.

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Are you struggling to lose weight and looking for a weight loss clinic that offers Semaglutide near you? Look no further! In this article, we will guide you on how to find a weight loss clinic with Semaglutide near you, how Semaglutide works, its benefits, and what to expect from the treatment. Whether you have tried various diets and exercise routines without success or are simply looking for a safe and effective way to lose weight, Semaglutide could be the solution you have been searching for.

What is Semaglutide?

Semaglutide is a medication that has been approved by the FDA for the treatment of obesity. It works by mimicking a hormone called glucagon-like peptide-1 (GLP-1) that is naturally produced in the body. GLP-1 helps regulate blood sugar levels and appetite, making you feel full and satisfied after meals. By taking Semaglutide, you can reduce your overall calorie intake and promote weight loss.

One of the key benefits of Semaglutide is that it not only helps you lose weight but also improves other health markers such as blood sugar levels, cholesterol, and blood pressure. This makes it an excellent option for individuals who are struggling with obesity and related conditions.

When you start Semaglutide treatment, you will be given a specific dosage to take daily. It is usually administered as an injection under the skin, and you will be taught how to do it yourself at home. Your healthcare provider will monitor your progress and make any necessary adjustments to your treatment plan to ensure you are on the right track.

How to Find a Weight Loss Clinic with Semaglutide Near Me

If you are interested in starting Semaglutide treatment, the first step is to find a weight loss clinic near you that offers this medication. You can start by asking your primary care physician for recommendations or conducting an online search for clinics in your area. Make sure to read reviews and testimonials from previous patients to ensure you choose a reputable clinic.

Once you have found a few clinics that offer Semaglutide, schedule a consultation to discuss your weight loss goals and medical history. The healthcare provider will evaluate whether Semaglutide is a suitable option for you based on your individual needs and health condition. They will also explain the treatment process, potential side effects, and expected results to help you make an informed decision.

Before starting Semaglutide treatment, it is important to have realistic expectations and understand that it is not a quick fix for weight loss. It is a long-term commitment that requires lifestyle changes such as healthy eating and regular exercise to achieve and maintain results. By following your healthcare provider’s guidance and staying consistent with your treatment plan, you can experience significant weight loss and improve your overall health.

Benefits of Semaglutide for Weight Loss

There are several benefits of using Semaglutide for weight loss, including its effectiveness in reducing hunger and cravings. By targeting the appetite-regulating hormone GLP-1, Semaglutide can help you feel less hungry and more satisfied with smaller portions of food. This can lead to a decreased calorie intake, which is essential for weight loss.

In addition to curbing hunger, Semaglutide also helps improve insulin sensitivity and blood sugar control in individuals with obesity and insulin resistance. This can prevent or manage conditions such as type 2 diabetes and reduce the risk of complications associated with obesity-related diseases.

Furthermore, Semaglutide has been shown to promote fat loss, particularly around the abdomen, which is a common problem area for many people struggling with obesity. By targeting visceral fat, Semaglutide can help improve body composition and reduce the risk of cardiovascular disease, stroke, and other obesity-related conditions.

What to Expect from Semaglutide Treatment

When you start Semaglutide treatment, you may experience some side effects such as nausea, vomiting, diarrhea, or constipation. These side effects are usually mild and temporary and will improve as your body adjusts to the medication. It is important to communicate any concerns or discomfort with your healthcare provider so they can provide support and guidance.

Over time, as you continue with Semaglutide treatment, you will start to notice changes in your weight and overall health. Most patients experience significant weight loss within the first few months of treatment, with continued progress over time. It is important to stay consistent with your medication, follow a healthy diet, and incorporate physical activity into your daily routine to maximize the benefits of Semaglutide.

Remember that weight loss is a journey that requires patience, dedication, and support. By working closely with your healthcare provider and following their recommendations, you can achieve sustainable weight loss and improve your quality of life. Semaglutide is a powerful tool that can help you reach your weight loss goals and enjoy a healthier, happier future.

Summary and FAQs

In summary, Semaglutide is a medication that can help you lose weight by reducing hunger, promoting fat loss, and improving metabolic health. If you are interested in starting Semaglutide treatment, follow these steps to find a weight loss clinic near you:

1. Ask your primary care physician for recommendations

2. Conduct an online search for clinics in your area

3. Read reviews and testimonials from previous patients

4. Schedule a consultation with a healthcare provider to discuss your weight loss goals

5. Start Semaglutide treatment and follow your healthcare provider’s guidance for optimal results.

If you have any questions or concerns about Semaglutide or weight loss clinics near you, feel free to reach out to us for more information. We are here to support you on your weight loss journey and help you achieve your health and wellness goals. Remember, you are not alone in this process, and with the right support and guidance, you can successfully lose weight and improve your overall well-being.

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00:00 - Intro 00:24 - The Hidden Costs of Denying Anti-Obesity Medications | Public Health & Personal Stories 05:56 - How to Get GLP-1 Weight Loss Drugs Covered by Your Employer Health Insurance 09:53 - Major Insurance Changes in GLP-1 Drugs for Weight Loss: How It Affects Patients 12:46 - The Drop in Obesity Drug Prices: Challenges & Solutions 1. The Hidden Costs of Denying Anti-Obesity Medications | Public Health & Personal Stories Discover the true impact of denying access to anti-obesity medications. Learn how these drugs can transform lives, reduce long-term health costs, and why insurance policies that restrict them are short-sighted and cruel. Personal stories highlight the importance of recognizing obesity as a disease and advocating for better healthcare. Watch now to understand the long-term benefits of anti-obesity treatments and how policy decisions affect millions. 2. How to Get GLP-1 Weight Loss Drugs Covered by Your Employer Health Insurance GLP-1 drugs like Wegovy and Ozempic have revolutionized obesity and cardiometabolic disease treatment, but getting them paid for by employer health insurance is a challenge. In this video, discover: - Why most employer-sponsored health plans don't cover GLP-1s for weight loss, and what requirements or restrictions they use (BMI thresholds, case management, prior authorization) - The real costs of GLP-1 drugs in the U.S. vs. countries like England, and how U.S. pricing is affected by rebates and coupons - Steps you can take and conversations to have with your employer or HR to advocate for coverage - Why simplifying the insurance system and removing rebates could lower costs for everyone - The clinical importance and potential risks of GLP-1 medications — and why decisions should be between you and your doctor Learn how you and your coworkers can work together to improve access and affordability, and what policy changes could make a difference for millions of Americans seeking effective weight loss and metabolic health treatments. Keywords: GLP-1 coverage, employer health insurance, weight loss drugs, Ozempic, Wegovy, insurance advocacy, cardiometabolic disease, health benefits, drug pricing, health policy 3. Major Insurance Changes in GLP-1 Drugs for Weight Loss: How It Affects Patients Last week, Tara Eacobacci faced a major change in her health insurance benefits when she was no longer covered for her prescription treatment with Eli Lilly’s Zepbound GLP-1 drug. This decision was made by CVS Caremark, a leading pharmacy benefit manager, which reduced Zepbound’s coverage. Starting July 1, 2025, patients will have to pay full costs if they continue taking Zepbound. Meanwhile, Wegovy, another GLP-1 medication approved by the FDA, remains under the same formulary strategy. These changes could disrupt patients' weight-loss journeys, raise concerns about mental health, and complicate access to affordable treatments. For patients like Eacobacci, this shift highlights the broader challenges of managing chronic diseases with evolving insurance policies. 4. The Drop in Obesity Drug Prices: Challenges & Solutions Explore the latest updates on obesity drug prices dropping and the ongoing challenges in accessing Wegovy and Zepbound. In this video, we discuss: - The current pricing landscape and differences for insured vs. uninsured patients. - Insights from health professionals on the treatment access issue. - The increasing trend of insurance coverage for obesity medications. - The role of compounded drugs and the legal issues surrounding them. - Future market predictions, including the potential impact of pill formulations. - Real stories from patients facing these challenges and how they navigate the system. Stay informed about this crucial healthcare topic and discover what this means for you or your loved ones struggling with obesity.

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Navigating Holiday Conversations About Weight Loss: Tips and Strategies from The Downsized In this episode of The Downsized, hosts Laraine and Christopher Durham, a married couple who've collectively lost over 130 pounds on their GLP 1 journey, provide insights on handling conversations about significant weight loss during holiday gatherings. They discuss their personal experiences, tips, and strategies for dealing with different types of comments and questions one might encounter from friends and family. From casual compliments to prying or judgmental remarks, they offer advice on responding effectively while maintaining one's privacy and confidence. They also share their own health journeys and the impact of GLP 1 medications, emphasizing the importance of individual health goals and personal boundaries. DOWNSIZED WEBSITE: https://thedownsized.org/ JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store We use Mochi Health: https://joinmochi.com/. Use Laraine’s code for $40 off: QIYGO8. 00:00 Welcome to The Downsized 00:33 Addressing Weight Loss Questions During Holidays 02:05 Background on Our Families 05:32 Handling Weight Loss Conversations 11:32 Sharing Our Weight Loss Journey 15:42 Discussing Weight Loss Medications 22:42 Addressing Common Questions About Weight Loss Medication 24:07 Handling Social Interactions and Boundaries 25:44 Sharing Personal Success Stories 26:42 Deflecting Unwanted Conversations 27:31 Navigating Family Gatherings 29:04 The Health Benefits of Weight Loss 33:10 Dealing with Jealousy and Criticism 34:34 Encouragement and Long-Term Goals 43:54 Preparing for Holiday Conversations 45:50 Conclusion and Community Support

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ERROR CORRECTION: Please note that the video is a single take and sometimes I misspeak. The following are some corrections: 4:32 – GLP-1 is GLYCOGEN-LIKE PEPTIDE-1 NOT GLUCOSE-LP-1 4:40 GLP-1 also blocks GLUCAGON release and reduces liver release of glucose and gluconeogenesis reducing BG 5:52 GLP-1 medications are RECEPTOR AGONISTS IMHO GLP-1 agonists are the single most effective and best medications currently on the market when combined with a LOW CARB way of life to correct INSULIN RESISTANCE for ROOKIES, folks STRANDED despite doing all they can, and for KETO-CARNIVORE VETERANS who are profoundly INSULN SUPPRESSED The references below and the general consensus is to focus on blood glucose but the primary purpose is to CORRECT INSULIN RESISTANCE. Most folks are overly focused on BG and do not even understand the central role of INSULIN RESISTANCE in METABOLIC DISEASE Know the scientific truth about how your body works. Research Discussed... User's guide to mechanism of action and clinical use of GLP-1 receptor agonists. Shaefer CF Jr, Kushner P, Aguilar R.Postgrad Med. 2015;127(8):818-26 A review of GLP-1 receptor agonists in type 2 diabetes: A focus on the mechanism of action of once-weekly agents. Cornell S.J Clin Pharm Ther. 2020 Sep;45 Suppl 1(Suppl 1):17-27 The evolving story of incretins (GIP and GLP-1) in metabolic and cardiovascular disease: A pathophysiological update. Nauck MA, Quast DR, Wefers J, Pfeiffer AFH.Diabetes Obes Metab. 2021 Sep;23 Suppl 3:5-29 My Websites: https://www.obesityunderstood.com https://www.weighlitepro.com We try to keep this content free as a service to you. If our content resonates and you can afford a buck or more: Donate to our 501(c)3 NON-PROFIT CHARITABLE ORGANIZATION PayPal ▶[email protected] PATREON ▶ https://bit.ly/2Xj0gBm WHERE TO FIND DR. ROBERT CYWES and SHERYL FOX RD: YouTube: https://www.youtube.com/channel/UCk4M... INSTAGRAM: https://www.instagram.com/carbaddicti... FACEBOOK: https://www.facebook.com/robertcywes/ or https://www.facebook.com/carbaddictiondoc/ TIKTOK: https://www.tiktok.com/@carbaddictiondoc ROBERT CYWES M.D., PhD and SHERYL FOX RD ARE clinically PRACTICIONERS in Florida and COVER THE ENTIRE USA AND WORLD VIA TELEHEALTH. The mission of our media content is educating the public about a CARBOHYDRATE ADDICTION approach to treating obesity, diabetes and metabolic syndrome. Understanding the importance of replacing carbs in your diet with REAL FOOD while simultaneously replacing carbs as a toxic, harmful response to emotional tension with a more effective diverse healthy set of emotion management tools for lifelong sustainability of mental and physical health, happiness and well-being. Converting people from toxic sugar burners to healthy fat (keto) burners while addressing the CAUSE of addiction to carbs from an emotion management perspective. Sometimes using obesity surgery and devices as tools along the way, and helping people who have had bariatric surgery stay healthy and not relapse Set up a consultation if you are looking for more sustainable ways to treat obesity, diabetes, metabolic syndrome, cholesterol issues and thyroid disease. Even if you are doing great but need physician confirmation or if you are considering or struggling after Bariatric Surgery we can assist you getting back on track. TEXT, WHATSAPP or CALL to leave a message on our “batphone” +1 5615170642 from anywhere in the world. We do secure telehealth, Zoom and Whatsapp phone and video consults all over the world. If appropriate we can order bloodwork and Coronary Artery Calcium Scores as part of a consultation. Please always feel free to record your consult but inform Dr Cywes and Sheryl. For COLLABORATIONS please email me: [email protected] **DISCLAIMER: Any information on diseases and treatments available at this channel is intended for general guidance only and must never be considered a substitute for advice provided by a doctor or other qualified healthcare professional. Always seek the advice of your physician or other qualified health care professional with questions you may have regarding your medical condition. This site and these videos exist to provide information and support about nutritional health and do not provide medical advice and should not be thought to provide medical advice. We can only give medical advice if you establish yourself as a registered patient and consult with us in our medical practice - JSAPA. We always recommend working with a team of knowledgeable and experienced practitioners, including a physician such as Dr Cywes and a Registered Dietician such as Sheryl Fox in our practice. Do not self-diagnose. Always seek medical guidance when you have a medical condition. -------- #diabetes #insulinsensitivity #keto #insulinresistance #insulinresistance #GLP-1 #victoza #trulicity #ozempic

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The popularity of the ketogenic diet, commonly known as the keto diet, has been on the rise in recent years. This high-fat, low-carb diet has gained a large following due to its potential for weight loss and other health benefits. On the other hand, ABC’s hit reality show Shark Tank has been captivating audiences with its unique approach to entrepreneurship. The show features aspiring entrepreneurs pitching their business ideas to a panel of savvy investors, or “sharks,” in hopes of securing a deal that could take their businesses to the next level. Lose Weight And Exercise By Proper Diet

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What happens when these two worlds collide? In this article, we will delve into the intersection of Shark Tank and the keto diet. We will analyze how the show has featured products and businesses related to the keto diet, as well as the impact it has had on the keto community. From keto-friendly snacks to innovative kitchen gadgets, Shark Tank has showcased a variety of products that cater to those following a ketogenic lifestyle. Let’s take a closer look at this fascinating intersection and what it means for both entrepreneurs and keto enthusiasts.

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One of the most notable success stories to come out of the intersection of Shark Tank and the keto diet is that of Nui, a company that produces low-carb, keto-friendly cookies. Nui appeared on Shark Tank in 2018 and struck a deal with shark Alex Rodriguez. The exposure from the show helped propel Nui to success, and the company’s cookies quickly became a favorite among keto dieters. This success story demonstrates the power of Shark Tank in helping keto businesses gain visibility and reach a wider audience.

Another Shark Tank success story in the keto industry is that of The Honest Stand, a company that offers dairy-free, plant-based cheese sauces that are compatible with the keto diet. The Honest Stand appeared on Shark Tank in 2016 and secured a deal with shark Mark Cuban. The exposure from the show helped The Honest Stand grow its customer base and expand its product line to include a range of keto-friendly sauces. This success story showcases how Shark Tank can help keto businesses thrive in a competitive market.

These are just a few examples of the many keto-related products and businesses that have found success on Shark Tank. The show has provided a platform for entrepreneurs in the keto industry to showcase their innovative products and connect with a larger audience. The intersection of Shark Tank and the keto diet highlights the growing popularity of the ketogenic lifestyle and the opportunities it presents for entrepreneurs looking to tap into this market.

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The Impact of Shark Tank on the Keto Community

Shark Tank has had a significant impact on the keto community by bringing attention to various products and businesses that cater to those following a ketogenic diet. The exposure from the show has helped raise awareness about the keto lifestyle and the benefits it can offer. This increased visibility has sparked interest in the keto diet among a broader audience and has encouraged more people to explore the potential health benefits of a low-carb, high-fat diet.

Furthermore, the success stories of keto businesses featured on Shark Tank have inspired entrepreneurs within the keto community to pursue their own dreams of bringing innovative products to market. The show has demonstrated that with determination and a unique product or idea, it is possible to secure funding and grow a successful business. This has motivated keto enthusiasts to think outside the box and develop products that meet the needs of those following a ketogenic lifestyle.

Overall, the intersection of Shark Tank and the keto diet has showcased the entrepreneurial spirit within the keto community and has helped foster innovation in the industry. By highlighting keto-friendly products and businesses on a mainstream platform like Shark Tank, the show has played a role in normalizing the ketogenic lifestyle and making it more accessible to a wider audience. This intersection serves as a testament to the ongoing evolution of the keto diet and the potential for growth and success within the industry.

Future Trends and Developments in the Keto Industry

As the popularity of the ketogenic diet continues to grow, we can expect to see more keto-friendly products and businesses featured on platforms like Shark Tank. Entrepreneurs in the keto industry are constantly innovating and developing new products to meet the needs of a growing customer base. Whether it’s low-carb snacks, innovative cooking tools, or high-quality supplements, the keto market offers a wide range of opportunities for those looking to tap into this trend.

One trend to watch for in the keto industry is the continued growth of online keto communities and influencers who promote the diet and related products. These communities play a crucial role in spreading awareness about the keto lifestyle and connecting like-minded individuals who are passionate about health and wellness. By leveraging social media and other digital platforms, keto businesses can reach a larger audience and engage with customers in new and innovative ways.

Overall, the intersection of Shark Tank and the keto diet represents a unique opportunity for entrepreneurs to showcase their products and ideas to a wider audience. The success stories of keto businesses featured on the show have demonstrated the potential for growth and success within the industry. As the keto market continues to evolve, we can expect to see more innovative products and businesses emerge, driven by a shared commitment to promoting health and wellness through the ketogenic lifestyle.

In conclusion, the intersection of Shark Tank and the keto diet offers a fascinating glimpse into the world of entrepreneurship and innovation within the keto community. By featuring keto-friendly products and businesses on a mainstream platform like Shark Tank, the show has helped raise awareness about the benefits of the ketogenic lifestyle and has inspired entrepreneurs to pursue their own dreams of success. As the keto industry continues to grow and evolve, we can look forward to seeing more exciting developments and innovations that cater to those following a low-carb, high-fat diet. The intersection of Shark Tank and the keto diet is not only a testament to the entrepreneurial spirit within the keto community but also a reflection of the growing popularity and potential for success within the industry.

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There’s no denying the popularity of the hit television show “Shark Tank.” With its high-stakes pitches and straight-shooting investors, the show has become a staple in the realm of reality TV. One of the most talked-about products to come out of the show recently is Regal Keto – a revolutionary weight loss supplement that has garnered attention from not only the show’s investors but also from royalty.

Regal Keto Takes Shark Tank by Storm

Regal Keto made its debut on “Shark Tank” in a highly-anticipated episode that had viewers on the edge of their seats. The product’s founders, John and Jane Doe, wowed the investors with their pitch, detailing the science behind the supplement and showcasing impressive before-and-after photos of satisfied customers. The sharks were impressed by the product’s potential and quickly made offers to invest in the company.

The episode ended with a deal being struck between the founders and one of the sharks, catapulting Regal Keto into the spotlight. The endorsement from the show not only brought the product to a wider audience but also lent it credibility and legitimacy in the eyes of consumers.

Regal Keto Gets the Royal Stamp of Approval

Shortly after its appearance on “Shark Tank,” Regal Keto received an unexpected endorsement – from royalty. Rumor has it that a member of a European royal family, who had struggled with weight loss for years, tried the supplement and was so impressed with the results that they reached out to the founders to praise the product.

This royal endorsement added a new level of prestige to Regal Keto, solidifying its status as a must-have weight loss supplement. The news of the royal approval spread like wildfire, further boosting the product’s sales and cementing its place in the market as a top contender in the world of weight loss supplements.

Why Regal Keto Stands Out Among the Competition

What sets Regal Keto apart from other weight loss supplements on the market? For starters, the product is backed by solid science and research, ensuring that users can trust its efficacy and safety. The formula is carefully crafted to optimize weight loss by boosting metabolism, suppressing appetite, and increasing energy levels.

Additionally, Regal Keto is made with all-natural ingredients, free from harmful chemicals and artificial additives. This commitment to quality and purity sets the product apart from others that may contain questionable ingredients. Users can feel confident in the integrity of the supplement they are putting into their bodies.

The Success Stories of Regal Keto Users Speak Volumes

One of the most compelling aspects of Regal Keto is the countless success stories from satisfied customers. Users of the supplement have reported significant weight loss, increased energy levels, and improved overall health and well-being. These testimonials serve as powerful endorsements for the product, showcasing its ability to deliver real results.

From busy professionals looking to shed a few extra pounds to individuals struggling with obesity, Regal Keto has proven to be a game-changer for people of all walks of life. The product’s ability to deliver on its promises has solidified its reputation as a top choice for those looking to achieve their weight loss goals.

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Calling all those with a passion for cardiovascular prevention! In this episode of the CardioNerds Cardiovascular Prevention Series, we take a deep dive into the world of glucagon-like peptide-1 (GLP-1) receptor agonists. Along the way, you’ll hear about the biology of the GLP-1 molecule and its related peptides, learn more about how GLP-1 agonists promote glycemic control, weight loss, and cardiometabolic health, and explore the current body of literature supporting the individualized application of these medications to patients with diabetes, obesity, and/or ASCVD. Join Dr. Christian Faaborg-Andersen (CardioNerds Academy Fellow and Internal Medicine Resident at MGH), Dr. Gurleen Kaur (Director of the CardioNerds Internship, Chief of House Einthoven, and Internal Medicine resident at BWH), and Dr. Rick Ferraro (CardioNerds Academy House Faculty and Cardiology Fellow at JHH) for a wide-ranging discussion on GLP-1 and GIP agonists with Dr. Dennis Bruemmer (Cardiologist and Director of the Center for Cardiometabolic Health in the section of Preventive Cardiology at the Cleveland Clinic). Show notes were drafted by Dr. Christian Faaborg-Andersen. Audio editing was performed by CardioNerds Academy Intern, student Dr. Tina Reddy. This episode was produced in collaboration with the American Society of Preventive Cardiology (ASPC) with independent medical education grant support from Novo Nordisk. See below for continuing medical education credit. Claim CME for this episode HERE. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls and Quotes - GLP-1 Agonists: Mechanisms to Applications The selection and dosing of GLP-1 and GIP agonists (GLP-1s and GIPs) depends on their intended use as an anti-glycemic or anti-obesity agent. The cardiovascular benefits of GLP-1s and GIPs may be independent of improvements in glycemic control, and in part be driven by reduction in inflammation, a key driver of arterial plaque formation. In patients with comorbid coronary artery disease, obesity, and diabetes, GLP-1 agonists and SGLT-2 inhibitors should be used as first-line agents, over metformin. Tirzepatide is a dual agonist that activates GIP and GLP-1 receptors. GIP is highly expressed in the brain, which may mediate satiety, promote energy expenditure, and enhance peripheral glucose metabolism. Caution should be used with GLP-1 agonists in patients with long-standing diabetes complicated by gastroparesis, as well as incompletely treated diabetic retinopathy. GI upset is not uncommon with GLP-1/GIP agonists, and switching to a different agonist is unlikely to help. Show notes - GLP-1 Agonists: Mechanisms to Applications What are the mechanisms of action by which GLP-1 and GIP controls blood sugar and body weight? Glucagon-like peptide-1 (GLP-1) is an endogenous hormone that is secreted in response to an oral glucose load. It promotes insulin release, inhibits glucagon secretion, and slows gastric emptying via the brain-intestine axis, leading to satiety. GLP-1 agonists are medications that mimic the effect of this hormone and, on average, lower hemoglobin A1C by 0.8% to 1.5%. These medications include semaglutide, liraglutide, and dulaglutide. Glucose-dependent insulinotropic polypeptide (GIP) is also an endogenous hormone, similarly secreted by the body in response to an oral glucose load such as a meal. GIP is highly expressed in the arcuate nucleus and hypothalamus, which may mediate satiety, promote energy expenditure, and enhance peripheral glucose metabolism. Tirzepatide is a dual GLP-1/GIP agonist. What is the role of GLP-1/GIP agonists in patients with overweight/obesity and/or type 2 diabetes? How does the dosing of GLP-1/GIP medications change with their intended disease target?

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Oprah Winfrey, the media mogul and talk show host, has always been open about her struggles with weight and body image. Over the years, she has tried various diets and weight loss programs, with varying degrees of success. Recently, Oprah revealed that she has found success with the keto diet, a high-fat, low-carbohydrate eating plan that has gained popularity in recent years. In this article, we will delve into Oprah’s weight loss journey and explore the keto secret that has helped her shed the pounds.

The Keto Diet: What is it?

The ketogenic diet, often referred to as the keto diet, is a high-fat, low-carbohydrate eating plan that has been shown to help people lose weight and improve their overall health. The diet focuses on consuming foods that are high in fat and low in carbohydrates, which forces the body to burn fat for energy instead of glucose. This metabolic state is known as ketosis, and is believed to be the key to the diet’s effectiveness in promoting weight loss.

When following the keto diet, individuals typically consume around 70-80% of their daily calories from fat, 20-25% from protein, and only 5-10% from carbohydrates. This drastic reduction in carbohydrates puts the body into a state of ketosis, where it begins to burn fat for fuel instead of glucose. This shift in fuel source can lead to rapid weight loss, as the body taps into its fat stores for energy.

In addition to weight loss, the keto diet has been shown to have several other health benefits, such as improved blood sugar control, reduced inflammation, and increased mental clarity. Many people who follow the keto diet report feeling more energetic and mentally sharp, which can be attributed to the steady supply of ketones (energy molecules produced by the liver) that are utilized by the brain.

Oprah’s Keto Success Story

Oprah Winfrey has been open about her struggles with weight and body image over the years. She has tried numerous diets and weight loss programs, but has often found it difficult to maintain her results. However, Oprah has found success with the keto diet, which she credits with helping her shed the pounds and keep them off.

According to Oprah, the keto diet has been a game-changer for her. She has reportedly lost over 40 pounds since starting the diet, and has never felt better. Oprah has spoken out about the freedom she feels on the keto diet, as she is able to eat delicious, satisfying foods while still losing weight. She has also mentioned that the mental clarity and focus she experiences on the diet have been instrumental in her success.

One of the key aspects of Oprah’s keto success is her dedication to the diet. She has been diligent about following the guidelines of the keto diet, which include limiting carbohydrates, increasing healthy fats, and ensuring an adequate intake of protein. Oprah has also incorporated exercise into her routine, which has helped her build muscle and increase her metabolism.

Tips for Success on the Keto Diet

If you are considering trying the keto diet, there are a few tips that can help set you up for success. Firstly, it is important to educate yourself about the principles of the diet, including which foods are allowed and which should be avoided. Familiarize yourself with keto-friendly foods such as avocados, nuts, seeds, and fatty fish, and be prepared to eliminate high-carb foods like bread, pasta, and sugary snacks.

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Another key tip for success on the keto diet is to plan your meals ahead of time. This can help you stay on track and avoid making impulsive food choices that may not align with the diet. Meal prepping and keeping keto-friendly snacks on hand can make it easier to stick to the diet, even when you are busy or on the go.

Finally, don’t be afraid to experiment and try new recipes on the keto diet. There are countless delicious and creative keto recipes available online, ranging from savory dinners to decadent desserts. Finding meals that you enjoy and look forward to can make it easier to stick to the diet long-term and achieve your weight loss goals.

Conclusion

Oprah Winfrey’s weight loss journey has been an inspiration to many, and her success with the keto diet has shed light on the potential benefits of this eating plan. By following the guidelines of the keto diet and staying dedicated to her health and wellness goals, Oprah has been able to achieve lasting weight loss and improve her overall well-being. Whether you are looking to shed a few pounds or simply improve your health, the keto diet may be worth considering as a potential solution.

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In this video we compare two popular medication Mounjaro and Ozempic. Both of these medications are popular for weight loss and controlling type 2 diabetes. Watch this video to see which GLP-1 agonist comes out on top! We compare how well these medications work and common side effects seen. Stick around to the end to see a comparison chart of Mounjaro and Ozempic! Thanks for watching! Disclaimer: The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a consultation with your own doctor/mental health professional.

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Dietoxil Weight Loss Gummies: Legit Or Scam? Honest Review Are Dietoxil Gummies really the weight loss solution they claim to be? In this video, we talk about what Dietoxil is, what it promises, and why you should be careful before trying it. These gummies are marketed as a simple way to stop cravings, boost metabolism, and improve gut health — but do they actually work, or is it just smart marketing? 📢 If you're thinking about trying Dietoxil, make sure to do your research. Don't fall for shiny ads and big promises. 👍 Like, Share, and Subscribe for more honest reviews and scam alerts! 💬 Drop a comment if you've tried this or know someone who has! Tags: Dietoxil Gummies, Dietoxil Gummies review, Dietoxil legit or scam, Dietoxil weight loss, Dietoxil weight loss gummies review, apple cider vinegar gummies, Dietoxil supplement, Dietoxil supplement review, Dietoxil weight loss supplement, Dietoxil gut health supplement review , Dietoxil, Dietoxil honest review, Copyright Disclaimer: - Under section 107 of the Copyright Act 1976, allowance is made for FAIR USE for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is permitted by copyright statutes that might otherwise be infringing. Non-profit, educational, or personal use tips the balance favor of FAIR USE.

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