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#mounjaro #zepbound Day 758 on Zepbound | Hi, I’m Amy! In this Week 108 update, I’m celebrating 70+ pounds lost with tirzepatide and over a year of maintenance. Plus, shoutouts to Shirley (6.5 lbs down at 71!) and Chris (61 lbs lost). Let’s keep thriving together! WHO AM I? Hi! I’m Amy and I tried for over 30 years to get healthy. That changed on December 1, 2022. Thanks Mounjaro! Since Day 1, I have shared my journey on this amazing life-changing medicine. I love researching and bringing relevant topics to our channel! I’m thanking God for all the blessings that this community & life brings! Thanks for watching! Much ❤️, Amy Amy’s Weight Loss 5’8” *Goal 158* ◆MONTH 1 (Start 218, End 195, 23 lbs lost, BMI 35) ◆MONTH 2 (Start 195, End 184, 11 lbs lost) ◆MONTH 3 (Start 184, End 175, 9 lbs lost, BMI 29) ◆MONTH 4 (Start 175, End 170, 5 lbs lost, BMI 27) ◆MONTH 5 (Start 170, End 167, 3 lbs lost) ◆MONTH 6 (Start 167, End 158, 9 lbs lost) HIT GOAL WEIGHT! ◆MONTH 7 GOAL MET! 158 lbs Maintenance Begins ◆MONTHS 8-18 MAINTENANCE! 145-155 lbs maintained for 16 months!! Amy is not a medical professional, so please refrain from substituting the content of this video and website for professional medical guidance. The materials provided here are intended solely for educational purposes. It is important that you seek advice from your healthcare provider for any medical concerns or inquiries. ✴️ connect, support, live zoom info @ www.patreon.com/amydenae

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Board-certified gynecologist @KarenTangMD dives into the topic of PCOS, one of the most common yet often misunderstood conditions affecting millions of women worldwide. She joins Hers Chief Medical Officer Dr. Jessica Shepherd on The Hers Podcast to break down PCOS symptoms, from irregular periods to hormonal imbalances, and discuss how PCOS can impact everything from fertility to metabolic health. They also discuss PCOS weight loss, PCOS inflammation, treating PCOS, and more. Tune in as Dr. Tang and Dr. Shepherd discuss what women need to know while navigating this condition and seeking to understand their bodies better. 2:09 What Is PCOS? 4:57 Does PCOS Cause Weight Gain? The PCOS and Insulin Resistance Connection 8:43 PCOS Diet 15:23 GLP-1 Medications and PCOS 18:29 PCOS Symptoms 26:20 PCOS and Pregnancy 30:40 PCOS Diagnosis & Treatment 35:30 Hormone Replacement Therapy for PCOS Want to learn more? Check out these articles. PCOS Symptoms, Causes, Treatment & More: https://www.forhers.com/conditions/pcos-polycystic-ovary-syndrome How to Lose Weight With PCOS: https://www.forhers.com/blog/pcos-and-weight-loss PCOS and Hair Loss—Why It Happens & How to Treat It: https://www.forhers.com/blog/polycystic-ovarian-syndrome-hair-loss #PCOS #PCOSWeightLoss #PCOSDiagnosis #TheHersPodcast Subscribe to Hers on YouTube: https://www.youtube.com/@forhers?sub_confirmation=1 Why Hers? ✨Affordable, personalized treatment plans ✨100% online process, including ongoing care and support ✨Free, discreet shipping to your door, if prescribed Connect with Hers on social: Facebook: https://www.facebook.com/wearehers X: https://x.com/wearehers Instagram: https://www.instagram.com/hers/ TikTok: https://www.tiktok.com/@hers This podcast is for informational purposes only and should not be considered medical advice. Dr. Jessica Shepherd and guests of The Hers Podcast are not providing personalized medical, health, or treatment recommendations. Always talk to your doctor about the risks and benefits of any treatment. The views, thoughts, and opinions expressed by guests are their own and do not necessarily reflect those of Dr. Shepherd, The Hers Podcast, or Hers.

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In this episode, host Jen shares her transformative health journey, delving into her experiences with GLP-1 medications, dietary adjustments, and the significance of mindful eating and label reading. Jen opens up about managing health conditions like diabetes and PCOS, highlighting the importance of aligning medications with health goals. She unpacks the impact of “sugar-free” and “keto-friendly” foods, often filled with hidden artificial sweeteners, and stresses the importance of reading the first five ingredients to better understand what's on your plate. Key points include her journey with intermittent fasting, protein intake for muscle maintenance, and the surprising health benefits of incorporating lemon into her diet despite dental health concerns. Jen also addresses product marketing, critiquing labels like “sugar-free” and “low-carb” and encourages listeners to approach dietary choices with moderation and awareness. By sharing her own initial missteps, she offers a grounded perspective on finding foods that help avoid bloating and fatigue and emphasizes seeking natural sources of vitamins over supplements. This episode serves as both a guide and encouragement for anyone navigating their own health journey, with Jen’s insights into balancing dietary habits, the value of electrolytes, and why it’s essential to tailor nutrition choices to fit individual needs. Follow Jen here! https://www.instagram.com/mommajenzhere/?hl=en https://www.tiktok.com/@UCxTL9fnEJI24vH3PjQ2u90g More on Jen here: https://beacons.ai/mommajenzhere?fbclid=PAZXh0bgNhZW0CMTEAAaZRdzZWWwhjFXHtNn-0phJSIr0X5tOHN6jMiXlvwEMM7Ur7iqjJ3D1z6ow_aem_LPyac68gGNU8NOyZ7Snd6w

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Understanding Weight Loss Medications

In today’s increasingly health-conscious society, weight management remains a significant concern for many individuals. While diet and exercise are the foundational elements of any weight loss journey, advancements in medical treatments have introduced various pharmaceutical options that can aid in the process. Among these treatments, GLP-1 receptor agonists have garnered significant attention, yet they are not the only options available for those seeking to lose weight. In fact, there exists a myriad of non-GLP-1 weight loss medications that cater to varied needs and preferences. Understanding these alternatives can empower individuals to make informed decisions regarding their weight loss strategies.

The effectiveness of weight loss medications often hinges on several factors, including an individual’s health status, the presence of coexisting medical conditions, and personal lifestyle preferences. Non-GLP-1 medications come in different classes, each with its unique mechanism of action and potential benefits. These drugs provide alternatives for those who may not have responded favorably to GLP-1 medications or for those who may not be ideal candidates for these treatments.

This article will explore seven notable non-GLP-1 weight loss medications, highlighting their mechanisms, benefits, potential side effects, and overall suitability for various individuals. With this information, readers can better understand which options align with their health goals and needs, ultimately aiding in their journey toward effective weight management.

1. Orlistat: Blocking Fat Absorption

Orlistat is a well-established weight loss medication that acts by inhibiting the absorption of dietary fats in the intestines. This mechanism is crucial for individuals who find it challenging to manage their fat intake through dietary changes alone. When consumed with meals, Orlistat works to block approximately 25% of the fat consumed from being absorbed, which can significantly contribute to weight loss over time. It is available both as a prescription medication and an over-the-counter product known as Alli.

One of the primary benefits of Orlistat is its ability to promote weight loss without directly affecting appetite. Instead of suppressing hunger, Orlistat’s unique mechanism allows individuals to continue eating a varied diet while simply reducing the number of calories absorbed from fat. This can make the medication an appealing option for people who prefer not to restrict their food choices drastically while managing their weight. However, it is essential to make healthier dietary choices, as the effectiveness of Orlistat is maximized when combined with a balanced, reduced-calorie diet.

<pDespite its benefits, Orlistat is not without side effects. Common gastrointestinal effects, such as oily stools, flatulence, and urgency in bowel movements, can occur, particularly when high-fat meals are consumed. These side effects can be uncomfortable and may discourage some individuals from continuing the medication. Additionally, patients using Orlistat should be aware of the potential for malabsorption of fat-soluble vitamins, necessitating supplementation to ensure adequate nutrition. Overall, Orlistat can be a viable option for individuals looking for a non-GLP-1 medication to enhance their weight loss journey.

2. Phentermine: Appetite Suppression

Phentermine is one of the most commonly prescribed weight loss medications in the United States. Classified as an appetite suppressant, Phentermine works by stimulating the release of norepinephrine in the brain, which helps signal a feeling of fullness. This property makes it particularly useful for individuals who struggle with overeating or impulsive eating behaviors. Typically prescribed for short-term use, Phentermine is intended for individuals with a body mass index (BMI) of 30 or greater, or 27 or greater if other weight-related health issues are present.

<pThe appeal of Phentermine lies in its quick results, as many users report significant weight loss within the first few weeks of treatment. While the results can be motivating, it's worth noting that Phentermine is most effective when combined with a comprehensive weight loss plan that includes lifestyle modifications, such as improved dietary habits and increased physical activity. The ultimate goal is to establish long-term habits that promote sustained weight management beyond the course of medication.

<pHowever, Phentermine also comes with a potential for misuse and dependency, which is a concern for healthcare providers. Common side effects include insomnia, dry mouth, and increased heart rate, making it crucial to monitor patients closely while they are using this medication. Due to its stimulant properties, Phentermine is not suitable for individuals with a history of heart disease, high blood pressure, or certain mental health conditions. Therefore, it is essential to undergo a thorough medical evaluation before starting Phentermine to ensure it is a suitable option for weight loss needs.

3. Naltrexone-Bupropion: Dual Mechanism

Naltrexone-bupropion, marketed under the brand name Contrave, is a unique weight loss medication that combines two drugs with previously established uses. Naltrexone is often used for addiction treatment, while bupropion is an antidepressant. Together, they work synergistically to help control cravings and reduce appetite. By acting on the brain’s reward system, this medication addresses not only the physiological aspects of eating but also the emotional triggers that can lead to overeating.

<pClinical studies have shown that individuals taking Naltrexone-Bupropion can achieve more substantial weight loss compared to placebo treatments. One of the key advantages of this medication is that it does not require drastic changes to one’s diet, making it easier for individuals to incorporate into their daily life. The dual mechanism offers a comprehensive approach to weight management, targeting both hunger and emotional touchpoints that can lead to unhealthy eating patterns.

<pHowever, Naltrexone-Bupropion is not suitable for everyone. Patients with a history of seizures or eating disorders may face increased risks if they use this medication. Additionally, side effects can include nausea, constipation, and headache, which may diminish as the body adjusts to the treatment. Importantly, this medication requires a supportive framework to be effective, including behavioral therapy or dietary changes to achieve lasting results. When used correctly, Naltrexone-Bupropion can provide a valuable tool in the weight loss arsenal for individuals facing complex challenges.

4. Liraglutide: A Different Approach to Weight Management

Liraglutide, while a GLP-1 receptor agonist, also has unique applications outside the traditional context of GLP-1 medications for diabetes and weight loss. Liraglutide has been approved for weight management under the brand name Saxenda. It mimics the incretin hormone GLP-1, regulating appetite and promoting feelings of fullness after meals. Despite being in the same class as GLP-1 medications, Liraglutide’s approach and effectiveness can differ significantly.

<pSaxenda is specifically dosed for weight management and has shown considerable success in clinical trials where participants experienced significant reductions in body weight when following a caloric-restricted diet and exercise. Unlike traditional GLP-1 treatments for diabetes, Saxenda focuses solely on weight loss mechanisms, allowing for broader access among individuals not diagnosed with type 2 diabetes. This expands the available options for weight loss therapies.

<pThe administration of Liraglutide is done via a daily self-injection, which may deter some individuals due to the need for a needle. The most common side effects include gastrointestinal symptoms such as nausea and vomiting. As with any medication, individuals contemplating using Liraglutide should consult healthcare providers to assess their suitability and potential drug interactions. Overall, Liraglutide presents another viable option for people seeking effective weight management solutions that diverge from traditional weight loss medications.

5. Metformin: Beyond Diabetes Management

Metformin is a well-known medication primarily used to manage type 2 diabetes. However, over the years, research has emerged demonstrating its potential for weight management in non-diabetic individuals. Metformin works by improving insulin sensitivity, decreasing hepatic glucose production, and reducing intestinal absorption of glucose. These actions can contribute to modest weight loss in individuals who struggle with insulin resistance or overweight conditions.

<pOne of the key advantages of Metformin is that it is often well-tolerated, with fewer gastrointestinal side effects compared to other weight loss medications. This makes it an attractive option for individuals looking for an adjunct to weight management without the potential adverse effects associated with other pharmacological interventions. Furthermore, Metformin is sometimes prescribed to individuals with polycystic ovary syndrome (PCOS) to help manage both symptoms and weight.

<pHowever, Metformin is not a quick-fix solution for weight loss. The weight loss associated with Metformin use tends to be gradual and occurs alongside lifestyle changes. Because of its primary function in managing diabetes, it is not specifically designed as a weight loss drug, leading some experts to question its appropriateness as a primary treatment for obesity. Nonetheless, Metformin presents an option for patients who may benefit from its dual action of controlling blood sugar while promoting gradual weight loss.

Addressing Common Concerns and Questions

In summary, the landscape of weight loss medications is diverse, and non-GLP-1 alternatives offer a variety of options designed to meet different health needs. While medications such as Orlistat, Phentermine, Naltrexone-Bupropion, Liraglutide, and Metformin have proven effective for many individuals, they are not one-size-fits-all solutions. It is vital for those considering weight loss medications to consult with healthcare professionals to determine which options may be most beneficial based on their health status, preferences, and goals.

Individuals often have concerns regarding side effects, longevity of treatment, and potential interactions with other medications. The aforementioned medications can carry different side effects, ranging from gastrointestinal impacts to stimulant-related symptoms. A thorough discussion with a healthcare provider can address these concerns, helping individuals understand the risks and benefits associated with each option.

<pOverall, the journey towards effective weight management can be complex and may require a multifaceted approach that combines pharmacological treatment with lifestyle changes. Understanding the range of available options, including non-GLP-1 weight loss medications, is crucial for making informed decisions that align with personal health goals. As the field of weight management continues to evolve, staying informed will empower individuals to take effective steps toward achieving their desired outcomes.

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Planning for surgery while taking GLP-1s? Dr. Andres Sasson shares what you need to know before heading into a procedure — whether it’s minor or major. GLP-1 medications can impact anesthesia, digestion, and your overall surgical prep. In this quick video, Dr. Sasson explains how to talk to your care team and what to ask ahead of time. ✅ Timing GLP-1 doses before surgery ✅ What to tell your surgeon and anesthesiologist ✅ Why some surgeries may require pausing your meds ✅ General best practices for a smooth recovery 🔔 Subscribe for more real talk from people who take what they prescribe. 📅 Book a consult: https://lighthouseweightloss.janeapp.com 🌐 Learn more: https://www.lighthouseweightloss.com #GLP1 #SurgeryPrep #DoctorExplains #Ozempic #Mounjaro #Semaglutide #Tirzepatide #GLP1Safety

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