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Carlat Psychiatry News | Stimulant Fraud • Oral Ketamine • E-Cigarettes • Benzo Tapering • CBD 💡Subscribe to our newsletter: https://www.thecarlatreport.com/products ➡️Check out our website: https://www.thecarlatreport.com/ ================ Follow Carlat: 🔴SUBSCRIBE ► / @thecarlatreport ➡️Twitter: / CarlatPsych ================ References: Hines, Lindsey A et al. “Incident psychotic experiences following self-reported use of high- potency cannabis: Results from a longitudinal cohort study.” Addiction (Abingdon, England) vol. 119,9 (2024): 1629-1634. doi:10.1111/add.16517 Fucito, Lisa M et al. “Varenicline for E-Cigarette Cessation in Adults: A Preliminary Placebo- Controlled Randomized Trial.” American journal of preventive medicine vol. 67,2 (2024): 296- 298. doi:10.1016/j.amepre.2024.04.007 Glue, Paul et al. “Extended-release ketamine tablets for treatment-resistant depression: a randomized placebo-controlled phase 2 trial.” Nature medicine vol. 30,7 (2024): 2004-2009. doi:10.1038/s41591-024-03063-x Gundugurti, Prasad Rao et al. “Evaluation of the efficacy, safety, and pharmacokinetics of nanodispersible cannabidiol oral solution (150 mg/mL) versus placebo in mild to moderate anxiety subjects: A double blind multicenter randomized clinical trial.” Asian journal of psychiatry vol. 97 (2024): 104073. doi:10.1016/j.ajp.2024.104073 Rohde, Christopher et al. “A Nationwide Target Trial Emulation Assessing the Risk of Antidepressant-Induced Mania Among Patients With Bipolar Depression.” The American journal of psychiatry vol. 181,7 (2024): 630-638. doi:10.1176/appi.ajp.20230477 Tuisku, Anna et al. “Electronic Cigarettes vs Varenicline for Smoking Cessation in Adults: A Randomized Clinical Trial.” JAMA internal medicine vol. 184,8 (2024): 915-921. doi:10.1001/jamainternmed.2024.1822 Benzodiazapene Tapering Guidelines: https://downloads.asam.org/sitefinity-production-blobs/docs/default-source/guidelines/bzd-cpg-narrative-draft-for-public-comment.pdf?sfvrsn=6d96408_2 ================ 0:00 - Intro 0:29 DOJ Charges Telehealth Executives 1:55 Oral Extended Release Ketamine 3:29 MDMA Trials Suspended 04:43 Liquid Clonidine and Liquid Lithium 5:46 Benzodiazepine Tapering Guidelines 8:01 Antidepressants in Bipolar Disorder 10:52 Vaping Trials and Smoking Cessation 12:54 Brexpiprazole & Sertraline For PTSD 14:15 CBD Oil for Anxiety #MentalHealthNews #psychiatry #psychiatricmedications #psychnews #psychiatrynews #psychopharmacology #pmhnp #psychnp ================ In this episode, we explore nine groundbreaking stories in mental health and psychiatric medicine, covering everything from healthcare fraud to the latest advancements in drug trials. Healthcare Fraud Charges: The US DOJ has charged executives at Done, a California telehealth company, for allegedly prescribing 40 million Adderall pills without proper evaluation. Extended Release Oral Ketamine: New trials on an extended release oral ketamine show potential for treatment-resistant depression. (https://pubmed.ncbi.nlm.nih.gov/38914860/) MDMA-assisted Psychotherapy Setbacks: After FDA approval was pulled due to ethical concerns, can upcoming trials revive this promising therapy for PTSD? Liquid Formulations: Onyda is brand name for the new liquid Clonidine XR and the return of liquid lithium citrate offer new options for ADHD and bipolar patients. Benzodiazepine Tapering Guidelines: The American Society of Addiction Medicine's new draft guidelinesadvocate for a careful, patient-centric approach, especially for vulnerable populations. Antidepressants and Bipolar Disorder: A Danish study provides some reassurance about using antidepressants in bipolar disorder, but its methodology leaves some questions unanswered. E-Cigarettes vs. Chantix: A new trial finds nicotine e-cigarettes as effective as Chantix for smoking cessation, but flavored vape products and their health risks continue to spark debate. Brexpiprazole and Sertraline for PTSD: Brexpiprazole showing promise as an add-on treatment to sertraline, but will the FDA approve this new therapy? CBD Oil for Anxiety: A new phase 3 trial offers hope for treating anxiety with CBD oil, though its high cost rmay emain a barrier for many patients.

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When considering whether Purekana CBD Gummies are worth purchasing, it’s essential to weigh the cost against the potential benefits. While CBD products can be more expensive than traditional supplements, the quality and effectiveness of Purekana’s products may justify the price. Purekana is known for its commitment to transparency and quality, using third-party lab testing to ensure the purity and potency of their products.

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In conclusion, while individual experiences with CBD products may vary, Purekana CBD Gummies have garnered positive reviews from both consumers and industry professionals. With their high-quality ingredients, convenient dosing, and delicious flavors, Purekana CBD Gummies are a compelling option for those looking to explore the potential benefits of CBD in a fun and convenient way.