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Last updated on 2025-11-18

2025-11-18

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#prednisone #prednisonesideeffects #steroids #steroidsideeffects #glucocorticoid 📌Get your "Prednisone Checklist" today: https://prednisonepharmacist.com/prednisone-wellness-checklist/ This video explores the use of tirzepatide and other GLP-1 agonists as weight loss medications, particularly for individuals taking prednisone, a corticosteroid commonly associated with weight gain. It examines the interaction between these medications and how tirzepatide may help mitigate prednisone-induced weight gain. The video also delves into the mechanisms of action of GLP-1 agonists, ranks them based on their weight loss efficacy, and stresses the importance of consulting healthcare professionals before starting any treatment. Additionally, an herbal alternative to GLP-1 agonists is briefly mentioned as a potential option. Key Takeaways: 1. Tirzepatide and GLP-1 Agonists: The video discusses tirzepatide as a promising GLP-1 agonist for weight loss, especially for individuals taking prednisone, a corticosteroid known for causing weight gain. 2. Mechanisms of Action: GLP-1 agonists work by reducing appetite, slowing gastric emptying, and improving insulin sensitivity, helping counteract some of prednisone’s weight gain effects, like increased appetite and insulin resistance. 3. Efficacy of GLP-1 Agonists: Tirzepatide stands out for its effectiveness in weight loss, with patients losing 15-20% of their body weight. Other GLP-1 agonists like semaglutide and liraglutide also contribute to weight loss, though to varying extents. 4. Medical Consensus and Considerations: There is no clear consensus among rheumatologists about prescribing GLP-1 agonists for patients on prednisone, underscoring the need for healthcare professionals to tailor treatment based on individual needs. 5. Alternative Options: The video highlights the potential of an herbal alternative to GLP-1 agonists, offering individuals a weight management option without the high costs of pharmaceutical treatments. - Dr. Megan is the Prednisone Pharmacist who experienced side effects from a prescription drug called prednisone. Here she teaches tips to deal with side effects naturally. Every week Dr. Megan posts a new video with an answer to your burning prednisone questions. ✅ Get your Prednisone Checklist for the Top 7 Mistakes prednisone users make, plus 15 ways to counteract prednisone side effects: https://prednisonepharmacist.com/prednisone-wellness-checklist/ Need a way to give back what prednisone steals? Dr. Megan invented Nutranize Zone, which contains the 10 nutrients prednisone steals. The only supplement you need while on prednisone. https://nutranize.com/ Learn more at Dr. Megan's website with videos posted as in-depth blogs at prednisonepharmacist.com Follow Dr. Megan! Facebook: facebook.com/prednisonepharmacist Instagram: @prednisonepharmacist Book an appointment with Dr. Megan at https://calendly.com/prednisone/1 Write me! Dr. Megan 1400 Chapel St #343 Santa Clara, UT 84738

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Weight loss is a challenging journey for many individuals, with various factors coming into play when trying to shed those extra pounds. From diet to exercise, finding a solution that works best for you can be a daunting task. One potential option that has gained attention in recent years is the use of semaglutide, a medication originally developed to treat type 2 diabetes. Research has shown that semaglutide can also be effective in promoting weight loss when used at higher doses than those typically prescribed for diabetes management.

What is Semaglutide?

Semaglutide is a medication that belongs to a class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1 RAs). It is commonly used to lower blood sugar levels in individuals with type 2 diabetes by mimicking the effects of the GLP-1 hormone, which stimulates insulin secretion and inhibits glucagon secretion. In addition to its glucose-lowering effects, semaglutide has also been shown to suppress appetite and promote weight loss, making it a promising option for individuals looking to manage their weight.

When used at higher doses specifically for weight loss purposes, semaglutide is administered as a subcutaneous injection once a week. The medication works by affecting the appetite control center in the brain, leading to reduced food intake and increased feelings of fullness. This helps individuals consume fewer calories, leading to gradual but sustainable weight loss over time.

Studies have shown that semaglutide can lead to significant weight loss in individuals who are overweight or obese. In a clinical trial involving over 1,900 participants, those who received semaglutide lost an average of 15-20% of their body weight over the course of one year, compared to just 2-5% in the placebo group. This highlights the potential of semaglutide as an effective tool for weight management when used at the appropriate dose.

Starting Dose of Semaglutide for Weight Loss

When it comes to starting semaglutide for weight loss, it is important to follow the prescribed dosing regimen recommended by your healthcare provider. Typically, individuals begin with a lower dose of semaglutide and gradually increase the dosage over time to minimize side effects and maximize effectiveness. The starting dose of semaglutide for weight loss is usually 0.25 mg administered once a week for the first four weeks.

After the initial four-week period, the dose of semaglutide is increased to 0.5 mg once a week for another four weeks. This gradual dose escalation helps the body adjust to the medication and minimizes the risk of gastrointestinal side effects, which are common with GLP-1 RAs. If tolerated well, the dose of semaglutide can be further increased to 1.0 mg once a week, which is the highest dose approved for weight loss purposes.

It is important to note that the starting dose of semaglutide for weight loss may vary depending on individual factors such as age, weight, and overall health. Your healthcare provider will determine the appropriate dose for you based on these factors and closely monitor your progress to ensure the medication is safe and effective. It is crucial to follow your provider’s guidance and not adjust the dose on your own to avoid potential complications.

Benefits of Semaglutide for Weight Loss

There are several benefits to using semaglutide for weight loss, beyond just the numbers on the scale. In addition to promoting significant weight loss, semaglutide has been shown to improve various markers of health, including blood sugar levels, blood pressure, and cholesterol levels. This can help reduce the risk of developing obesity-related conditions such as type 2 diabetes, heart disease, and stroke.

Furthermore, semaglutide has been found to have a positive impact on quality of life by reducing feelings of hunger and cravings, which can make it easier to stick to a healthy diet and maintain long-term weight loss. The medication is also well-tolerated by most individuals, with the most common side effects being mild and transient gastrointestinal symptoms such as nausea, vomiting, and diarrhea.

Overall, semaglutide offers a comprehensive approach to weight management by targeting both appetite control and metabolic function. When used as part of a holistic weight loss plan that includes diet, exercise, and behavioral changes, semaglutide can help individuals achieve and sustain their weight loss goals in a safe and effective manner.

Considerations Before Starting Semaglutide

Before starting semaglutide for weight loss, it is important to discuss with your healthcare provider to determine if the medication is right for you. Individuals with a history of pancreatitis, thyroid cancer, or certain gastrointestinal disorders may not be suitable candidates for semaglutide due to potential risks associated with the medication. Your provider will assess your medical history and current health status to make an informed decision about the use of semaglutide.

It is also essential to be aware of the potential side effects of semaglutide and how to manage them effectively. Gastrointestinal symptoms are the most common side effects experienced with semaglutide, but they typically improve over time as the body adjusts to the medication. If you experience severe or persistent side effects, it is important to contact your healthcare provider for guidance on how to proceed.

Additionally, it is crucial to commit to lifestyle changes such as healthy eating and regular physical activity while taking semaglutide for weight loss. The medication is most effective when used in conjunction with a balanced diet and exercise plan, as these factors play a significant role in long-term weight management. Your provider can help you develop a personalized weight loss strategy that incorporates semaglutide as part of a comprehensive approach to achieving your goals.