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Is it a good idea to be losing fat fast? Are there risks to aggressive fat loss such as regaining all the weight back? Subscribe here https://www.youtube.com/subscription_center?add_user=shockingfit Online Coaching now available: https://www.tomic.com/contact/ So you want to lose fat? Is it better to aggressive for a faster cut or take the slow and steady approach? There's a big myth out there that fat loss should always be a slow process. A lot of coaches give out a recommendation that everyone should be losing 0,5 - 1 lbs per week and just go with the slow and steady approach. The same coaches will say that if you go for faster weight loss that there will be a greater risk of regaining the weight. However, this isn't always supported by the scientific literature. Example of studies showing that faster weight loss was successful: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692623/ https://www.ncbi.nlm.nih.gov/pubmed/20443094 https://www.nejm.org/doi/full/10.1056/NEJMsa1208051 On the other hand, we have a lot of gurus taking it to the other extreme recommending all sort of nonsense diets such as detoxes, juice cleanses and a lot of other potential harmful dietary protocols. To learn more about the detoxing is a scam I highly recommend you to check out examine.com/blog/detoxes-an-undefined-scam/ There are a time and place for an aggressive diet, and in some cases, this is the most favorable approach. What is a fast, aggressive approach? Typically, we would define the diet as aggressive if you're going for above 25% of your calories in a deficit. Additionally, we could also define it as aiming to lose more than 1.5% of your body weight per week. One excellent example of a scientifically backed "crash" diet is Lyle McDonald's Rapid Fat Loss Handbook https://www.bodyrecomposition.com/the-rapid-fat-loss-handbook/ Both fast and slow fat loss have their pros and cons, and that's something we want to look at to be able to choose which one is better for us. The three factors to consider when deciding between fast fat loss vs. slower fat loss: 1 - Your psychology Are you the type of person who gets motivated by thinking big? Do you find big goals exciting? Or do you care more about the process? Are you more process, or goal oriented? Do short term results keep you motivated or do you get inspired by thinking about the long term success? These are some of the questions to ask yourself. Additionally, some people love a more rigid restrictive diet plan because it gives them more sense of control. And if you strive in such an environment, a low-calorie diet might be the right thing for you. 2 - Your lifestyle Are you living a busy, stressful lifestyle? An aggressive diet will add more stress to your life, and if you're someone who's already under a lot of pressure, this is probably not a good idea. On the other hand, if you're a part-time student with a lot of free time to manage your nutrition going a bit more aggressive might just be the right thing for you. Think about how much space you have in your life right now. If you're juggling a lot of things at once, it's probably best to take the slow and steady approach. 3 - Your physique There's a category of individuals for which the aggressive diet (losing anywhere above 1.5% of BW / week) isn't a good idea. These would be already lean individuals at 10% body fat or lower, and athletes who need to maintain maximum performance. (https://www.ncbi.nlm.nih.gov/pubmed/25028999) If you're someone who can already see a six pack it's probably not a good idea to aim for very fast fat loss, losing arouse 0,5% of your body weight per week will help minimize muscle loss. On the other hand, if you're someone who has a lot of fat to lose (you can't see your abs) then you can go more aggressive. The more fat there is to mobilize the less there's risk for muscle loss. Hope you enjoyed the quick update. As always, post any questions you have in the comments below! And I'll see you in the next video! -Mario Online Coaching: https://www.tomic.com/contact/ For more fitness, nutrition, and personal development tips check out: Facebook: https://www.facebook.com/MarioTomicOfficial Instagram: https://instagram.com/mariotomich Website: https://www.tomic.com Music: DEAF KEV - Invincible https://www.youtube.com/watch?v=J2X5mJ3HDYE Follow DEAF KEV: Facebook https://www.facebook.com/officialDEAFKEV YouTube https://www.youtube.com/user/ATMDubstep

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Semaglutide has been gaining attention for its potential as a weight loss treatment. Originally developed for managing diabetes, this medication has shown promising results in clinical trials for individuals looking to lose weight. In its injectable form, semaglutide has already been approved by the FDA for weight management. However, researchers are now exploring the possibility of developing a pill form of semaglutide for easier administration and increased accessibility.

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One of the key benefits of a pill form of semaglutide is convenience. Unlike the injectable version, which requires regular injections, a pill can be taken orally, making it more user-friendly for individuals who may be hesitant about needles. This could potentially increase the number of people who are willing to try semaglutide as a weight loss treatment, ultimately leading to better outcomes for those struggling with obesity.

In addition to convenience, a pill form of semaglutide may also offer improved adherence to the medication regimen. For some individuals, the process of preparing and administering injections can be daunting and time-consuming. A pill form would eliminate this barrier, making it easier for patients to consistently take their medication as prescribed. This could lead to more effective results in terms of weight loss and overall health improvement.

Another advantage of a semaglutide pill form is the potential for better absorption and bioavailability. When taken orally, medications are absorbed through the gastrointestinal tract and enter the bloodstream more efficiently compared to injections, which may have variability in absorption rates. This could result in a more predictable and consistent response to the medication, leading to more reliable outcomes for patients using semaglutide for weight loss.

Challenges and Considerations

While the development of a pill form of semaglutide holds promise, there are also challenges and considerations that need to be addressed. One concern is the stability and bioavailability of the medication in pill form. Ensuring that the pill maintains its efficacy and is absorbed effectively by the body will be critical in the success of this new formulation.

Another challenge is the potential for gastrointestinal side effects. Semaglutide works by slowing down digestion and increasing feelings of fullness, which can lead to side effects such as nausea, vomiting, and diarrhea. It will be important for researchers to optimize the formulation of the pill to minimize these side effects while still maintaining the medication’s effectiveness for weight loss.

Additionally, the cost of a pill form of semaglutide may be a barrier for some individuals. The injectable version of semaglutide can be expensive, and it is likely that a pill form would also come with a significant price tag. This could limit access to the medication for those who need it most, especially if insurance coverage is limited or unavailable.

Future Directions and Potential Impact

Despite these challenges, the development of a pill form of semaglutide for weight loss has the potential to revolutionize the treatment of obesity. With its proven efficacy in clinical trials and the convenience of oral administration, this new formulation could help address the growing epidemic of obesity and improve the health outcomes of millions of individuals worldwide.

As researchers continue to explore the feasibility of a pill form of semaglutide, it will be important to consider how this medication can be integrated into existing weight loss programs and guidelines. Collaboration between healthcare providers, pharmaceutical companies, and patients will be key in ensuring that this new treatment option is accessible, affordable, and effective for those in need.

In conclusion, the development of a pill form of semaglutide for weight loss represents a significant advancement in the field of obesity treatment. With its potential for increased adherence, better absorption, and improved convenience, this new formulation has the potential to make a meaningful impact on the health and well-being of individuals struggling with obesity. While there are challenges to overcome, the promise of semaglutide as a pill form is an exciting development that offers hope for a healthier future.

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In this episode, I’m joined by Shaun Noorian—engineer, entrepreneur, and CEO of Empower Pharmacy, the largest compounding pharmacy in the world. With compounded GLP-1s making headlines and lawsuits from Big Pharma intensifying, Shaun joins me to pull back the curtain on the regulatory, financial, and ethical storm brewing behind the scenes. Are compounded GLP-1s legal? Safe? Who controls drug pricing in the U.S., and why are Americans paying 10x more than Europeans for the same medication? And most importantly—what does all this mean for access, affordability, and patient care? This episode is a wake-up call. If you care about transparency in medicine, patient rights, or access to life-saving medications, don’t miss this one. We cover: - Why compounded GLP-1s are under attack—and what the FDA’s recent moves really means - How Big Pharma sets drug prices—and why Americans pay up to 10x more than other countries - The legal battle over semaglutide, regulatory capture, and the influence of pharmaceutical lobbying - How compounding pharmacies offer personalized care and expand access to life-saving medications - What’s next for patients, clinicians, and the future of affordable medicine in the U.S. Who is Shaun Noorian? Shaun Noorian is the founder and CEO of Empower Pharmacy, the largest compounding pharmacy and 503B outsourcing facility in the United States. A fierce advocate for patient access and affordable care, Shaun has become a leading voice on the role of compounding in medicine and the urgent need for reform in pharmaceutical pricing and regulation. Forever Strong Summit 2025: Can’t make it to Houston on April 27th? Grab a Virtual “LIVE Access” Ticket and stream every keynote, panel, and breakthrough moment from the Forever Strong Summit 2025—live from your laptop, wherever you are. You’ll get front-row access to leaders like Dr. Don Layman, Rich Diviney, and Evy Poumpouras—plus priority access to all the recordings so you can revisit the insights anytime.Get your ticket now! https://drgabriellelyon.com/forever-strong-summit-2025/ This episode is brought to you by: Puori – Code DRLYON for 20% off sitewide! → https://puori.com/DRLYON Our Place - Code DRLYON for 10% off – https://fromourplace.com BON CHARGE – Code DRLYON for 15% off! → https://boncharge.com/DRLYON MUD\WTR - Code DRLYON for up to 43% off – http://mudwtr.com/DRLYON Find Shaun Noorian at: LinkedIn - https://www.linkedin.com/in/shaun-noorian X(Twitter) - http://x.com/shaunnoorian Empower Pharmacy - https://www.empowerpharmacy.com/ Find me at: Instagram: @drgabriellelyon TikTok: @drgabriellelyon Facebook: facebook.com/doctorgabriellelyon YouTube:youtube.com/@DrGabrielleLyon X (Twitter): x.com/drgabriellelyon Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/ Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page Get my book – https://drgabriellelyon.com/forever-strong/ Timestamps: 00:00 – Introduction: Why compounded GLP-1s are in the crosshairs 03:45 – Drug shortages, compounding access, and the rise of semaglutide 08:30 – Why patients flock to compounded medications (and who’s trying to stop it) 12:10 – Eli Lilly lawsuit and Big Pharma’s monopoly playbook 17:05 – Price fixing, international pricing gaps, and the $500/month illusion 21:40 – Regulatory capture: How the FDA, pharma, and lobbying intertwine 26:30 – What compounding pharmacies actually do—and why safety concerns are overblown 30:15 – The April Fool’s FDA warning letters: coincidence or coordinated attack? 35:50 – Can personalized medicine really be considered “dangerous”? 41:00 – What the media gets wrong—and how pharma shapes the narrative 47:00 – Are compounded GLP-1s banned? Sorting fact from fiction 53:25 – What’s next: state-level restrictions, 503B regulations, and the future of patient care Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions. Music from #InAudio: https://inaudio.org/ END OF THE BATTLE - Infraction

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