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🌟 Welcome to Downsized Live with Laraine and Christopher Durham! 🌟 Set sail with us as we broadcast live from the MSC Seascape, cruising through the blue waters of the Caribbean! As we journey through this paradise, we’ll dive into the transformative world of GLP-1 weight loss. Having experienced the life-changing benefits of these medications firsthand, we’re eager to share our personal journey, along with practical tips and tricks, all while soaking up the sun on this stunning voyage. In this interactive session, we’ll answer all your burning questions about weight management with GLP-1 agonists like Mounjaro, Zepbound, Ozempic, Wegovy, Tirzepatide, and Semaglutide. Don’t miss out on this unique opportunity—bring your questions and join us live from the heart of the Caribbean, where the sea meets wellness on our path to better health! JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store/ Start your weight loss journey today! We use Mochi Health: https://joinmochi.com/. Use Laraine’s code for $40 off: QIYGO8. DOWNSIZED WEBSITE: https://thedownsized.org/
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Obesity specialist Dr Holly Lofton reveals how she chooses the right GLP-1 for each patient, and the importance of staying on label. https://www.medscape.com/viewarticle/1000524?src=soc_yt -- TRANSCRIPT -- Hi. I'm Dr Holly Lofton. I'm a board-certified obesity medicine specialist, and I direct the medical weight management program at NYU Langone Health. With all the excitement about GLP-1 agonists, I get many questions from providers about which antiobesity drug they should prescribe. I'll tell you the methods that I use to determine which drug is best for which patient. Of course, we want to make sure that we're treating the right condition. If the patient has type 2 diabetes, we tend to give them medication that is indicated for type 2 diabetes. Many GLP-1 agonists are available in a diabetes version and a chronic weight management or obesity version. If a patient has diabetes and obesity, they can receive either one. If a patient has only diabetes but not obesity, they should be prescribed the diabetes version. For obesity without diabetes, we tend to stick with the drugs that are indicated for chronic weight management. Let's go through them. Exenatide. In chronological order of approval, the first GLP-1 drug that was used for diabetes dates back to exenatide (Bydureon). Bydureon had a partner called Byetta (also exenatide), both of which are still on the market but infrequently used. Some patients reported that these medications were inconvenient because they required twice-daily injections and caused painful injection-site nodules. Diabetes drugs in more common use include liraglutide (Victoza) for type 2 diabetes. It is a daily injection and has various doses. We always start low and increase with tolerance and desired effect for A1c. Liraglutide. Victoza has an antiobesity counterpart called Saxenda. The Saxenda pen looks very similar to the Victoza pen. It is a daily GLP-1 agonist for chronic weight management. The SCALE trial demonstrated 8%-12% weight loss with Saxenda. Those are the daily injections: Victoza for diabetes and Saxenda for weight loss. Our patients are very excited about the advent of weekly injections for diabetes and weight management. Ozempic is very popular. It is a weekly GLP-1 agonist for type 2 diabetes. Many patients come in asking for Ozempic, and we must make sure that we're moving them in the right direction depending on their condition. Semaglutide. Ozempic has a few different doses. It is a weekly injection and has been found to be quite efficacious for treating diabetes. The drug's weight loss counterpart is called Wegovy, which comes in a different pen. Both forms contain the compound semaglutide. While all of these GLP-1 agonists are indicated to treat type 2 diabetes or for weight management, Wegovy has a special indication that none of the others have. In March 2024, Wegovy acquired an indication to decrease cardiac risk in those with a BMI ≥ 27 and a previous cardiac history. This will really change the accessibility of this medication because patients with heart conditions who are on Medicare are expected to have access to Wegovy. Tirzepatide. Another weekly injection for treatment of type 2 diabetes is called Mounjaro. Its counterpart for weight management is called Zepbound, which was found to have about 20.9% weight loss over 72 weeks. These medications have similar side effects in differing degrees, but the most-often reported are nausea, stool changes, abdominal pain, and reflux. There are some other potential side effects; I recommend that you read the individual prescribing information available for each drug to have more clarity about that. It is important that we stay on label for using the GLP-1 receptor agonists, for many reasons. One, it increases our patients' accessibility to the right medication for them, and we can also make sure that we're treating the patient with the right drug according to the clinical trials. When the clinical trials are done, the study populations demonstrate safety and efficacy for that population. But if we're prescribing a GLP-1 for a different population, it is considered off-label use. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/1000524?src=soc_yt
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Sign up for our Nutrition program! It's available to anyone, anywhere: https://www.poundofcureweightloss.com/nutrition Managing Diabetes, Hair Loss, and GLP-1 Medication After Bariatric Surgery In the latest episode of the *Pound of Cure Weight Loss Podcast*, Dr. Matthew Weiner discussed key topics such as managing diabetes, hair loss after bariatric surgery, and the role of GLP-1 medications post-sleeve gastrectomy. The Best Diet for Diabetics Dr. Weiner corrected the misconception that diabetes is purely caused by carbohydrate overconsumption. He emphasized that the root cause is insulin resistance, not sugar intake. While cutting carbs can help, a plant-based diet rich in phytonutrients is ideal for managing diabetes. These nutrients, found in vegetables and fruits, improve insulin sensitivity, making them a critical component of a diabetic-friendly diet. Research also shows that consumption of animal fat is linked to insulin resistance, further stressing the need to prioritize a plant-rich diet over processed carbohydrates or animal protein. Addressing Hair Loss After Bariatric Surgery Hair loss is a common issue after bariatric surgery, typically occurring between three to six months post-op. Dr. Weiner explained that the rapid weight loss and nutritional deficiencies that follow surgery contribute to this. To minimize hair loss, it’s crucial to start taking bariatric multivitamins early, ideally as soon as the decision to undergo surgery is made. Iron and biotin (10,000 mcg daily) are particularly important in preventing hair loss. Additionally, Dr. Weiner recommended starting patients on minoxidil before surgery, as this can significantly reduce post-surgical hair thinning. Building up vitamin stores before surgery ensures that patients are less likely to suffer from deficiencies that can exacerbate hair loss. The Role of GLP-1 Medications After Sleeve Gastrectomy A major focus of the podcast was the use of GLP-1 medications, like semaglutide, after sleeve gastrectomy. Dr. Weiner explained that while sleeve surgery helps patients lose weight initially, up to 50% of patients experience weight regain. GLP-1 medications work by improving insulin sensitivity and lowering the body’s metabolic set point, which helps maintain weight loss. For many patients, especially those with higher BMIs, surgery alone is not enough. GLP-1 medications provide a long-term solution to weight maintenance by reducing insulin levels, which play a crucial role in fat storage. Dr. Weiner stressed that these medications should be seen as part of a lifelong treatment plan rather than a short-term fix. Conclusion Dr. Weiner emphasized that successful weight loss and diabetes management require a combination of treatments, including surgery, medication, and a plant-focused diet. Whether it’s preventing diabetes, minimizing hair loss, or maintaining weight loss with GLP-1 medications, a comprehensive, individualized approach is key to long-term success. Social Media: https://www.facebook.com/APoundofCure https://www.instagram.com/drmatthewweiner/?hl=en https://www.tiktok.com/creator-center/content Books: A Pound of Cure https://www.amazon.com/gp/product/B00AEYQYDE/ https://www.audible.com/pd/A-Pound-of-Cure-Audiobook/B09T777LSW How Weight Loss Surgery Really Works https://www.amazon.com/gp/product/1688128808/ The Bariatric Diet Guide and Cookbook https://www.amazon.com/Bariatric-Diet-Guide-Cookbook-Weight-Loss/dp/1615649875/ 00:00 Disclaimer 00:38 Introduction 1:04 How does a diet high in animal protein lead to diabetes? 4:43 How long should you be on the Metabolic Reset Diet? 7:31 Will all VSG patients need to be on GLP-1 medications at some point? 12:43 Is there anything I can do to minimize hair loss after surgery?
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Do These REALLY Guarantee Weight Loss? 🤔🔥" So many weight loss tips claim to be foolproof… but do they actually work? Let’s break it down and separate facts from fiction! Watch now to find out. #WeightLoss #FatLoss #HealthJourney #WeightLossTips #shorts #trendingshorts #trend #subscribe #short #viralshorts
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