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The Oyikey™ SMGT-GLP-1 Nano Microneedle Patch claims to be a game-changer for weight loss and blood sugar control. It promises to deliver semaglutide (GLP-1) through your skin without injections, helping with weight management and diabetes. But can this patch really do what it claims? In this video, we break down the truth behind Oyikey’s claims, fake endorsements, and why this could be a risky purchase. From questionable science to fake customer reviews, here’s why you should think twice before buying the Oyikey Microneedle Patch. Have you tried this product or something similar? Share your experience in the comments! Subscribe to Shop Critic for more honest reviews and scam alerts. #OyikeyMicroneedle #WeightLossScam #ShopCritic #HealthAlert Disclaimer: This video is for informational purposes only. The opinions shared are based on research and available facts. The product images in the video are for reference only and not intended to violate any copyrights.
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Dr David Johnson highlights new preoperative recommendations to protect against consequences of some diabetes and weight loss drugs that delay gastric emptying.
https://www.medscape.com/viewarticle/994762?src=soc_yt
-- TRANSCRIPT ---
Hello. I'm Dr David Johnson, professor of medicine and chief of gastroenterology in Eastern Virginia Medical School in Norfolk, Virginia.
Recent national media attention has focused on the gastrointestinal (GI) side effects of glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs are used to treat type 2 diabetes and weight loss. The GI side effects include nausea, vomiting, and gastroparesis-like symptoms.
I wanted to emphasize two key points especially important to clinicians providing this class of therapy.
One: Clinicians need to be increasingly aware of the potential GI side effects and inform their patients when they start to prescribe these medications.
And two: The American Society of Anesthesiologists (ASA) has recently released consensus-based recommendations for preoperative assessment and management of adults and children undergoing surgery who are taking these medications. The recommendations also apply to endoscopic procedures whereby anesthesia will be delivered.
Gastric Impact of GLP-1 Agonists
What are these GLP-1 agonists? The drugs for weight loss include liraglutide (Saxenda and Victoza) and semaglutide (Ozempic, Wegovy, Rybelsus, among others). The type 2 diabetes medications include semaglutide, dulaglutide (Trulicity), and exenatide (Byetta, Bydureon BCise), among others. They can be taken daily or by injection once a week.
The GLP-1 agonist drug class works at the GI level to increase insulin secretion and decrease glucagon release, both of which mediate glycemic control, particularly postprandially. The drugs slow the gastric motility through decreased peristalsis and increased tonic contractility of the pylorus, essentially causing a delay in gastric emptying.
Dr Michael Camilleri and his colleagues at the Mayo Clinic, in Rochester, Minnesota, conducted a small randomized, placebo-controlled double-blind study of the GLP-1 agonist liraglutide to investigate the mechanism of weight loss in patients who were overweight. They showed that there was a diminution in gastric emptying over 16 weeks in patients taking liraglutide. They found evidence of tachyphylaxis, but the rate of gastric emptying of solids remained slow compared with placebo, even at 16 weeks.
Despite the observed waning of the gastric impact, we just don't know how long significant side effects persist when patients stop the drug for good. There are some reports of patients with protracted symptoms a year or more after they've stopped their GLP-1 agonist medications.
Guidance for Preoperative Management
These drugs would commonly be reviewed before patients go through procedures, and we need to be better aware as we start to see these patients for endoscopy.
The ASA recommendations address the potential consequences of delayed gastric emptying and provide guidance for preoperative management of these drugs to prevent regurgitation and pulmonary aspiration of gastric contents.
In patients on daily dosing, the ASA recommends holding these agents the day prior to the procedure.
For patients on weekly dosing, the recommendations suggest withholding the dose a week before the procedure. Importantly, this should be in consultation with their diabetologist, just to assess any need for a bridging therapy to avoid hypoglycemia.
On the day of the procedure, if GI symptoms, such as severe nausea, vomiting, retching, abdominal pain, and bloating, are present, clinicians should consider delaying the elective procedure and discuss the risks of the potential risks for aspiration.
If the patient has no symptoms and the GLP-1 agonist has been withheld as advised, then you should proceed as usual.
But if the patient has no symptoms and has not held their GLP-1 agonist, you should proceed with what the anesthesiologists call the "full stomach" precaution, which considers patients at potentially high risk for aspiration. There's a way of checking for that. Some centers can do a quick ultrasound on the stomach and see if there's food, debris, or liquid, and if that is not the case, they could proceed with no delay. But if there is no way to check gastric contents, then you should manage accordingly, which may require intubation or postponing an elective procedure for another day.
These are new and changing issues. In our world as gastroenterologists, we should be considering — very strongly — mitigating strategies to protect the patients on this wonderful class of therapy. Sometimes these drugs can have significant side effects that we need to at least be aware of. Nothing is perfect, but let us be better informed.
https://www.medscape.com/viewarticle/994762?src=soc_yt
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What happens when weight loss becomes about more than just shedding pounds? Dive into personal GLP-1 journeys that redefine health and happiness. Laurie's life changed dramatically when diagnosed with diabetes, leading her to lose 130 pounds with GLP-1 medication.,For Lindsay, a GLP-1 helped shift her mindset from self-blame to realizing obesity was not her fault, reigniting her health passion.,Overcoming skepticism, Amy found new hope in GLP-1s, although she learned success requires more than medication alone.,Julie experienced a profound reduction in 'food noise', allowing her to focus on healing her relationship with food.,Bryan felt immediate changes in hunger and satiety, discovering the importance of discipline in managing cravings after starting GLP-1s.,Mireya faced challenges redefining her food relationship, showing how vacation meals became a struggle post-GLP-1 experience.,Tim's substantial weight loss helped him redefine self-image, revealing the impact of physical transformation on identity.,Darryl's weight loss journey spurred a search for identity beyond food and partying, emphasizing a new, healthier lifestyle.,Sally improved her nutrition and fitness, validating the importance of a holistic approach while on GLP-1 medication.,Kirk highlights the necessity of ongoing lifestyle changes with GLP-1s, reinforcing that healthy habits must persist for lasting results. #GLP1, #WeightLossJourney, #HealthTransformation
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GLP-1 agonist medications, such as semaglutide and tirzapetide are showing a lot of promise for fatty liver disease, also known as MASH (Metabolic Dysfunction-Associated Steatohepatitis). We present some of the key points from studies showing improvement of MASH in patients who are taking these medications. If you would like to set up an appointment with myself for a free consultation, check out my webpage at www.vitalitasmedical.com.
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If you feel like you are beginning to experience a fat loss/muscle building “plateau” in your training or nutrition goals, then you’ve come to the right place! In this video, Jordan discusses what it means to be in a “plateau” and how you can break from this point so that you can reach your goals. Let’s face it, we all at some point leave the honeymoon phase of training where progress begins to slow down and we are left battling with our emotions and questioning whether what we are doing is even working… Jordan stresses the importance of understanding that although progress has begun to slow down, that doesn’t mean that it is time to quit! If you have been following Mind Pump for some time then you may understand that our bodies are adaptation machines and it doesn’t take very long for our bodies to begin to get better at utilizing the stressors/energy that we give it. Here are some important points and quick tips mentioned in the video: - “Plateau” is different for all individuals - You are not going to lose weight every day - You are not going to get stronger after every workout - Don’t let your emotions keep you from staying consistent - Take the long-term approach with your health - Quitting WILL make you stop your progress When it comes to reaching your health goals, as much as it would be nice to see fast progress, progression realistically goes more up and down. There is only so much planning ahead you can do and there are too many variables in our lives that we rarely can completely control. What we can control is how we react emotionally to our progress. Instead of looking at progress slowing down as a reason to quit, look at it as an opportunity to learn more about what is happening with your body. One thing we know for sure is that consistency will bring you much more progression over a long period of time vs deciding to quit stopping your progress entirely. Sal, Adam, & Justin have also covered this topic entirely and here is the episode where you can dive deep and learn more: Episode #1095: How To Break Through A Plateau https://mindpumppodcast.com/1095-how-to-break-through-a-plateau/ If you enjoyed this video, here are some videos you might like: How To Lose Stubborn Body Fat! (TRY THIS!!) | Mind Pump https://www.youtube.com/watch?v=ws0BsMqtRkc How to Bench Press with Proper Form (AVOID MISTAKES!) https://www.youtube.com/watch?v=-MAABwVKxok&feature=youtu.be Why You Can't Lose The Last 5 Pounds (AVOID THESE) https://www.youtube.com/watch?v=82aG2OjDopU Big Thank you to Jordan Syatt for filming this video, be sure to check out his Instagram here: https://www.instagram.com/syattfitness/?hl=en LIKE this video if you learned something new. SUBSCRIBE if you’re ready for more valuable fitness content! COMMENT below what your experience has been going through a plateau. Subscribe to Mind Pump TV - https://goo.gl/h44uXg CONNECT WITH US: INSTAGRAM: http://bit.ly/mindpumpmedia TWITTER: http://bit.ly/2vN1qpE FACEBOOK: http://bit.ly/2vq95cd SHOP MIND PUMP: http://bit.ly/2uvQY6b PRIVATE FACEBOOK GROUP: http://bit.ly/2vuntia PODCAST: iTUNES - http://apple.co/2vMEPcA STITCHER - http://bit.ly/2hQSIAS
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Does Ikaria Juice Really Deliver on Its Promises? Are you searching for a natural solution to boost your health and vitality? Ikaria Juice has rapidly gained popularity among health enthusiasts, touted for its potential benefits in weight management and overall wellness. But does this juice live up to the hype, or is it just another fleeting trend? Ikaria Juice, inspired by the dietary habits of the inhabitants of Ikaria—a Greek island known for the longevity of its residents—claims to harness the power of natural ingredients to promote health and well-being. Advocates of the juice suggest it can aid in weight loss, improve digestion, and enhance energy levels. But let's delve deeper into whether these claims hold water. At the heart of Ikaria Juice's appeal is its formulation, which often includes a blend of fruits, vegetables, and herbs believed to possess health-boosting properties. These ingredients are rich in antioxidants, vitamins, and minerals, which are essential for combating oxidative stress, supporting the immune system, and improving metabolic function. The juice is often marketed as a holistic approach to health, aligning with the growing trend toward natural and organic products. However, the efficacy of Ikaria Juice depends largely on its ingredients and the individual's lifestyle. While the antioxidants in the juice can indeed contribute to better health, they are not a magic bullet. To truly benefit from Ikaria Juice, it should be part of a balanced diet and healthy lifestyle. Relying solely on the juice for weight loss or other health benefits may lead to disappointment, as it is not a substitute for a varied diet and regular physical activity. Scientific evidence supporting the specific claims of Ikaria Juice is still limited. While some studies suggest that the individual components of the juice can offer health benefits, more research is needed to conclusively prove its effectiveness as a whole. Consumers should be wary of exaggerated claims and consider the juice as a supplement rather than a cure-all. Incorporating Ikaria Juice into your daily routine can be a positive step towards better health, particularly if it encourages you to consume more fruits and vegetables. However, it's crucial to maintain realistic expectations. The juice may support your health journey, but it is not a replacement for comprehensive lifestyle changes. Are you ready to take control of your health and discover whether Ikaria Juice could be a beneficial addition to your routine? Share your thoughts and experiences below—let's start a conversation about how this juice has impacted your wellness journey. #IkariaJuiceTruth #healthjourney #longevitysecrets https://youtu.be/mugyErBBI1k
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Mediterranean Baked CodFresh, simple, and bursting with flavor! Ingredients: • 1 medium purple onion, sliced into half rings • 1/2 cup (80g) green olives, pitted • 1/2 cup (80g) black olives, pitted • 2 tbsp (20g) capers • 1 cup (150g) cherry tomatoes, halved (plus extra sprigs for garnish, optional) • 1 tsp dried oregano • 1 tbsp olive oil (plus extra for drizzling) • 4 cod fillets (about 6 oz/170g each) • Salt & pepper, to taste • 2 garlic cloves, unpeeled, lightly crushed (optional) Instructions: 1) Preheat oven to 400°F (200°C). 2) In a bowl, mix onion, olives, capers, halved cherry tomatoes, oregano, and 1 tbsp olive oil. (No salt here—capers add plenty!) 3) Spread the mixture in an oven-safe dish. 4) Season cod with salt and pepper, then place on top. Add garlic cloves and optional cherry tomato sprigs for flair. 5) Drizzle with olive oil. 6) Bake for 15-18 minutes, until the cod flakes easily. 7) Serve hot and enjoy the aroma! Tip: The garlic peel adds a subtle flavor without overpowering the dish. #diet #mediterranean #dietrecipes #fishrecipe
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What is GLP-1 and how does it help with weight loss? 🧬 Hormones like GLP-1, also known as glucose-like peptide, play a key role in reducing appetite and slowing digestion, signaling your brain that you're full. This makes it a powerful tool in weight loss by promoting a caloric deficit. Joe Rogan and Andrew Huberman often mention the benefits of peptides like GLP-1 agonists, which also help in reducing cardiovascular risks and improving overall health.
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