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Last updated on 2025-11-18

2025-11-18

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GLP-1 medications like Ozempic and Wegovy are revolutionizing obesity treatment, but a new University of Virginia study reveals a potential downside: They don’t significantly boost cardiorespiratory fitness (CRF)—a critical predictor of long-term health and longevity. 🔬 Key Findings: ✔️ GLP-1s cut fat but also muscle—up to 40% of weight loss is lean mass. ✔️ No clear improvement in VO₂ max (a key measure of heart/lung fitness). ✔️ Low CRF = higher mortality risk, even if weight drops. 💡 The Solution? Exercise & protein intake may help preserve muscle. New drugs in development could offset muscle loss. Doctors urged to screen patients for malnutrition risks before prescribing. #Ozempic #WeightLoss #Health #Fitness #MedicalResearch 💬 Would you take a GLP-1 drug knowing it might not improve fitness? 🔔 Subscribe for more science-backed health insights! ⚕️ Why This Matters: CRF (cardiorespiratory fitness) is a stronger predictor of lifespan than BMI. Muscle loss on GLP-1s could increase frailty and metabolic risks. Combining meds with exercise might be the missing key to full health benefits. Study Published in: The Journal of Clinical Endocrinology & Metabolism DOI: 10.1210/clinem/dgaf335

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GLP-1 agonists have been a breakthrough for the treatment of obesity, a global problem with serious health risks. While the benefits of these therapies are seen as outweighing the risks, there have been some concerns about the loss of muscle mass, particularly in older people using these drugs. iBio is developing next-generation obesity therapies that may be able to be used in combination with GLP-1 agonists or by themselves. Its lead experimental therapy is a myostatin inhibitor, part of a class of therapies that have been of interest to treat muscle wasting. We spoke to Martin Brenner, CEO and chief scientific officer of iBIO, about obesity, the limits of GLP-1 agonists, and the potential for myostatin inhibitors alone or in combination with GLP-1 agonists.

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🎙️ GLP-1 Medications: Protecting Your Kidneys in More Ways Than One These diabetes medications do more than lower blood sugar—they may actually protect your kidneys. GLP-1 receptor agonists reduce kidney inflammation, lower blood pressure, support weight loss, and may directly protect kidney cells. In one of my patients with stage 3 CKD and uncontrolled diabetes, we saw major improvements in her kidney markers after starting this therapy. ✨ This episode is your deep dive into how these medications could support your kidney health. 🎧 Tap the link in our bio to listen to the full podcast! #KidneyHealth #GLP1 #CKD #FunctionalMedicine #KidneyProtection

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Transformative Journey of Chrissy Metz

Chrissy Metz, an acclaimed actress known for her powerful performances, particularly in the hit television series “This Is Us,” has captured the hearts of millions not just with her talent but also with her authenticity. One of the most inspiring aspects of her life journey has been her ongoing struggle with weight and body image. At the start of 2024, Metz embarked on a transformative weight loss journey that saw her shed an astounding 100 pounds in just five months, bringing her weight down from 300 pounds to 200 pounds. This incredible feat not only highlights her dedication and resilience but also underscores the broader issues surrounding body positivity, self-love, and the challenges that many face when striving for health and wellness. Throughout her journey, Metz has become a beacon of hope and motivation for those who have faced similar struggles, leading them to rethink their approach to weight loss and self-acceptance. Her story emphasizes that overcoming hurdles is possible with the right mindset, support, and resources. In this article, we delve into the various elements that contributed to Metz’s success, exploring her motivations, the methods she adopted, the role of mental health, the impact of community and support, and ultimately, what her journey signifies for her fans and individuals grappling with similar issues.

Motivation Behind the Weight Loss

The motivation behind Chrissy Metz’s decision to lose weight stemmed from a combination of personal desire and professional demands. As an actress, Metz understood that her career often required her to be in the public eye, and the entertainment industry can be unforgiving in its standards of beauty and body image. This realization pushed her to consider making significant lifestyle changes. However, it wasn’t merely for the sake of appearances; Metz’s primary motivation was a desire for a healthier, more vibrant life. She recognized the potential health risks tied to being significantly overweight, including diabetes, heart disease, and other serious conditions. The transformative workout and dietary changes she embarked upon were not solely cosmetic, but rather a crucial step toward improving her overall well-being.

Moreover, Metz’s journey was fortified by her inability to ignore her health concerns any longer. Having faced her battles over the years, she decided to take charge of her life, aiming to set a positive example for her fans and the younger generation. This sense of responsibility fueled her drive to lose weight and transform her lifestyle. The support she received from her family and friends played a critical role in her motivation. Knowing that she had a support system, one that encouraged her decisions and celebrated her milestones, gave her the necessary push to remain committed to her weight loss journey, even through the hardest days when temptation might have been the easiest path to follow.

Ultimately, Metz discovered that motivation is not just about external validation from society or peers; it’s deeply rooted in self-love and respect. She realized the importance of nurturing her mental health throughout the weight loss process. A key lesson from her journey is that the road to meaningful change requires introspection, patience, and a clear understanding of one’s personal goals. Metz’s experience reinforces the idea that motivation can be a powerful catalyst for change, one that spurs individuals to confront their fears and make conscious decisions that lead to holistic improvement in their lives.

Methodology: Diet and Exercise Regimen

The methodology that Chrissy Metz adopted in her weight loss journey is a testament to the importance of combining diet, exercise, and lifestyle changes in achieving long-lasting results. Metz began her journey by working closely with health professionals, including nutritionists and fitness trainers, who provided valuable guidance on how to structure her diet and exercise regimen. One of the key components of her diet involved reducing caloric intake while still ensuring she received adequate nutrition. She incorporated a variety of fruits, vegetables, lean proteins, and whole grains into her meals, while limiting processed foods, sugars, and unhealthy fats.

Exercise played a pivotal role in Metz’s weight loss success. Initially, she started with moderate activities that were manageable and enjoyable, such as walking and light resistance training. This approach helped her build endurance and strength without overwhelming her body. As her fitness improved, she gradually increased the intensity and duration of her workouts, incorporating a mix of cardiovascular exercises, strength training, and flexibility routines. Visiting the gym became a vital part of her daily routine, transforming into a space for personal growth and empowerment. The diversity in her workouts not only kept her engaged but also provided physical and mental benefits that fueled her commitment to the weight loss process.

The pivotal aspect of Metz’s methodology was the creation of a balanced and sustainable lifestyle. She learned that quick fixes and fad diets typically yield only short-term results and can lead to cycles of yo-yo dieting. Instead, Metz focused on cultivating healthy habits that she could maintain in the long run. This included meal prepping, setting realistic fitness goals, and staying hydrated. Additionally, she prioritized getting ample sleep, recognizing the connection between rest and weight loss. Ultimately, Chrissy Metz’s journey serves as an inspiring example that achieving one’s weight loss goals requires a dedication to holistic health, with a balanced diet and consistent exercise forming the cornerstone for a successful transformation.

Mental Health and Self-Compassion

The journey of weight loss is often intertwined with mental health, and for Chrissy Metz, this connection became an essential element of her transformation. In a society that frequently emphasizes physical appearance, Metz has openly discussed the importance of nurturing one’s mental and emotional well-being throughout her weight loss adventure. One of the significant aspects of her approach was fostering self-compassion. Rather than indulging in negative self-talk or feelings of guilt regarding her body image, Metz practiced kindness towards herself. This shift in mindset enabled her to view her body through a lens of appreciation and gratitude, enhancing her self-esteem and motivation for change.

Moreover, Metz engaged in therapeutic practices, including cognitive behavioral therapy (CBT), to address any emotional eating triggers and to reinforce positive self-perception. Recognizing the psychological factors at play, she was able to equip herself with tools to manage cravings and overcome emotional setbacks. Metz understood that emotional healing was just as essential as physical transformation, and facing her emotional challenges head-on contributed significantly to her success. She emphasized the importance of seeking support, whether from friends, family, or mental health professionals, to navigate the complexities of self-image and weight loss.

Through her journey, Metz has inspired countless individuals to prioritize their mental health alongside their physical goals. She has shown that change is not always about numbers on a scale but rather about cultivating a healthy relationship with oneself. By highlighting the emotional struggles and triumphs associated with weight loss, Metz has encouraged others to embrace their own journeys with patience and self-love. Ultimately, her message serves as a powerful reminder that maintaining mental health is an integral part of any wellness journey, and it is vital to recognize that every individual’s path to transformation is uniquely their own.

The Role of Community and Support Systems

The role of community and support systems cannot be overstated in Chrissy Metz’s weight loss journey. She has often expressed gratitude for the friends and family who cheered her on during her transformation. This unwavering support was instrumental in keeping her motivated, especially on days when self-doubt crept in or when temptations seemed overwhelming. Surrounding oneself with positive influences can create an environment that fosters growth and accountability. Metz found comfort and encouragement in sharing her goals with those in her circle, allowing them to inspire her to stay committed to her journey.

In addition to her immediate support network, Metz connected with a broader community of individuals facing similar challenges, including fans, online groups, and fitness enthusiasts. Engaging with others on parallel journeys encouraged her to share stories, experiences, and techniques, further enhancing her resolve. This exchange of support helped demystify the weight loss process and emphasized that no one is alone in their struggles. Together, they celebrated victories, shared setbacks, and offered guidance, building a sense of camaraderie that is vital in any worthwhile endeavor.

Metz’s experience illustrates the importance of having someone to lean on during difficult moments. Sharing her journey through social media platforms allowed her to reach even wider audiences, ultimately building a community of encouragement and inspiration. The lessons she learned from others and in turn shared with her followers serve as valuable reminders that successful weight loss is often a communal journey. The relationships cultivated during this experience brought her not only companionship but also a deeper understanding of the importance of collaboration, empathy, and shared resilience in achieving one’s goals. This powerful sense of connectedness further empowered her identity beyond weight loss, allowing her to inspire others to pursue their own health journeys.

Insights from Chrissy Metz’s Weight Loss Journey

Reflecting on Chrissy Metz’s extraordinary weight loss journey offers invaluable insights for anyone seeking to make lasting changes in their lives. One of the most salient lessons is that transformation is possible, provided there is commitment, perseverance, and a strategic approach. Metz’s ability to shed 100 pounds in five months did not stem from a superficial desire for appearance; rather, it was driven by a profound commitment to changing her health trajectory for the better. Her story reminds us that it is never too late to take charge of one’s health and pursue transformation.

Another crucial insight is the significance of crafting a personalized plan. Metz’s journey exemplifies that there is no one-size-fits-all solution to weight loss. What works for one individual may not resonate with another. By working closely with health professionals who understood her unique needs, she created a roadmap that allowed her to focus on sustainable progress rather than quick fixes. This approach teaches the importance of seeking expert advice and being open to trial and error while discovering what lifestyle modifications work best for each individual.

Lastly, Metz’s journey emphasizes the multidimensional nature of successful weight loss. It serves as a reminder that mental and emotional well-being are integral components of physical health. The balance of nurturing one’s self-esteem, mental health, and holistic wellness provides a stronger foundation for long-term success. Chrissy Metz’s story is more than just a remarkable weight loss achievement; it is an inspiring narrative of resilience, vulnerability, and the triumph of the human spirit. Her journey will continue to inspire countless individuals to pursue their unique health paths while fostering self-compassion and community support.

Summary of Insights and Common Questions

In summary, Chrissy Metz’s remarkable weight loss journey provides a rich tapestry of lessons that resonate with many individuals striving for change. Several key takeaways emerge from her path, including the significance of intrinsic motivation, the methodical approach to diet and exercise, the need for mental health awareness, the crucial support of community, and the understanding that transformation is a multifaceted process. Each of these elements combines to create a holistic picture of how sustainable weight management can be achieved through discipline, self-care, and personal growth.

Common questions surrounding Metz’s weight loss journey may include inquiries about her specific diet plan or workout routine. While Metz has shared some general guidelines about her approach, it is essential to recognize that her journey is unique to her circumstances and needs. Individuals seeking to embark on similar paths should consult with healthcare professionals to develop a personalized plan that aligns with their goals and lifestyle. Additionally, questions often arise regarding the mental health aspects of weight loss. Metz emphasizes that emotional well-being is paramount, and seeking help, whether through therapy or through connecting with supportive communities, is vital for success.

Others might wonder about how to sustain weight loss after reaching their goals. Metz illustrates that the journey does not end with reaching a target weight; rather, it requires ongoing commitment to maintaining healthy habits while allowing for moments of indulgence. This balance is vital to avoid the cycles of yo-yo dieting that many individuals experience. Engaging with community support, setting new personal goals, and prioritizing self-love can further contribute to lasting success. Ultimately, Chrissy Metz’s journey serves as a source of inspiration and hope, encouraging individuals to embark on their personal transformations with determination, support, and a mindset of resilience.

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In this episode of Giggles & Glutes, we dive deep into the viral wellness product that’s sparked lawsuits and major controversy: Kourtney Kardashian’s “natural Ozempic” gummy — Lemme GLP-1 Daily. We break down the science of GLP-1 (glucagon-like peptide-1), the hormone targeted by prescription weight loss medications like Ozempic and Wegovy, and explore whether over-the-counter GLP-1 supplements actually deliver results — or just false hope. 💊 From ingredient breakdowns to dose requirements, we decode what makes a GLP-1 support supplement effective — and what makes it a total scam. ⚖️ We also explore the class-action lawsuits filed against Kourtney Kardashian’s Lemme brand in early 2025, the claims of false advertising, and why many consumers are now questioning celebrity-backed wellness products. 🔗 Related Links & Resources: • 🎥 James Welsh’s video: “Kourtney’s gummies vs. Ozempic… https://www.youtube.com/watch?v=Y_qZ7tBqkYA • 📰 The Independent: “Kourtney Kardashian’s Lemme supplement brand faces class action lawsuit…” https://www.independent.co.uk/life-style/health-and-families/kourtney-kardashian-lemme-gummies-lawsuit-b2601004.html • ⚖️ Top Class Actions: “Kourtney Kardashian’s Lemme falsely advertises weight loss supplement” https://topclassactions.com/lawsuit-settlements/lawsuit-news/kourtney-kardashians-lemme-falsely-advertises-weight-loss-supplement-class-action-alleges/ • 🧪 NutraIngredients-USA: “Lemme facing class action over GLP‑1 supplement claims” https://www.nutraingredients-usa.com/Article/2025/04/30/lemme-lawsuits-challenge-glp-1-supplement-claims/ ⏰ Timeline: 00:00 – Hook: The “natural Ozempic” gummy scandal 00:30 – James Welsh & Kourtney’s gummy story 01:30 – GLP‑1: gut hormone basics 03:00 – Ozempic/Wegovy vs supplements 04:15 – Ingredients that *might* work 05:30 – Top 3 GLP‑1 products reviewed 06:30 – The lawsuits explained 08:00 – Celebrity wellness pitfalls 09:30 – How to shop smart 11:00 – Final takeaways + share this 📺 Watch on YouTube 🎧 Listen on Spotify, Apple Podcasts & more 📲 Follow us on Instagram: @gigglesandglutes 💬 Comment below with your go-to high-protein meal or fav macro combo! Don’t forget to LIKE, SUBSCRIBE & SHARE this with a friend who’s ready to build a body they love. 💪🍽️ 👩🏽‍⚖️ Disclaimer: We always strive to share the most accurate information on a topic however this can be mixed with opinion and we maintain that all the views and opinions expressed in this video is just that.

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Das Frühstück ist die wichtigste Mahlzeit des Tages, insbesondere wenn man abnehmen möchte. Ein gesundes Frühstück liefert Energie für den Tag und verhindert Heißhungerattacken. Versuchen Sie zum Beispiel ein leckeres Avocado-Toast mit pochiertem Ei und Rucola. Die Avocado liefert gesunde Fette, das Ei hochwertiges Eiweiß und der Rucola viele Vitamine und Mineralstoffe.

Oder wie wäre es mit einem frischen Obstsalat mit griechischem Joghurt und Nüssen? Dieses Frühstück ist reich an Ballaststoffen, Proteinen und gesunden Fetten und versorgt Sie mit wichtigen Nährstoffen. Ein gesundes Frühstück sorgt dafür, dass Sie sich den Tag über satt und energiegeladen fühlen.

Eine weitere köstliche Option für ein gesundes Frühstück ist ein Chia-Pudding mit Beeren und Mandeln. Chiasamen sind reich an Ballaststoffen und Proteinen und helfen dabei, den Blutzuckerspiegel stabil zu halten. Die Beeren liefern Antioxidantien und die Mandeln gesunde Fette.

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Für das Mittagessen eignen sich leichte Gerichte, die sättigend sind und gleichzeitig nicht zu schwer im Magen liegen. Versuchen Sie zum Beispiel einen bunten Quinoasalat mit gegrilltem Gemüse und Hühnchen. Quinoa ist eine gute Proteinquelle und liefert viele Ballaststoffe, das gegrillte Gemüse enthält wichtige Vitamine und das Hühnchen hochwertiges Eiweiß.

Eine weitere gesunde Option für das Mittagessen ist eine Gemüsepfanne mit Tofu und Vollkornnudeln. Tofu ist eine gute pflanzliche Proteinquelle, Vollkornnudeln liefern komplexe Kohlenhydrate und das Gemüse ist reich an Vitaminen und Mineralstoffen. Diese Mahlzeit ist leicht verdaulich und trotzdem sehr nahrhaft.

Oder wie wäre es mit einer leichten Tomatensuppe mit Linsen und Spinat? Diese Suppe ist reich an Ballaststoffen, Proteinen und Vitaminen und wärmt an kalten Tagen von innen. Linsen sind zudem eine gute Eisenquelle und Spinat enthält viele Antioxidantien.

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Snacks sind oft die Achillesferse vieler Diäten, da sie schnell zu ungesunden Entscheidungen führen können. Doch mit den richtigen Snackideen können Sie auch zwischendurch gesund und genussvoll essen. Versuchen Sie zum Beispiel eine Handvoll Nüsse und Trockenfrüchte als gesunden Snack. Nüsse enthalten viele gesunde Fette und Proteine, Trockenfrüchte liefern schnelle Energie.

Oder wie wäre es mit einer Portion Hummus mit rohen Gemüsesticks? Hummus ist reich an Ballaststoffen und Proteinen, die Gemüsesticks enthalten viele Vitamine und Mineralstoffe. Diese Kombination sättigt und liefert wichtige Nährstoffe für zwischendurch.

Eine weitere gesunde Snackidee sind Reiswaffeln mit Avocadocreme und Cherrytomaten. Reiswaffeln sind leicht verdaulich und liefern komplexe Kohlenhydrate, die Avocadocreme enthält gesunde Fette und die Cherrytomaten liefern Vitamine und Antioxidantien.

Gesunde Abendessenrezepte

Das Abendessen sollte leicht und bekömmlich sein, um einen ruhigen Schlaf zu gewährleisten. Versuchen Sie zum Beispiel gegrillten Lachs mit gedünstetem Gemüse und Quinoa. Lachs ist reich an Omega-3-Fettsäuren, das gedünstete Gemüse liefert viele Vitamine und Quinoa ist eine gute Protein- und Ballaststoffquelle.

Oder wie wäre es mit einer vegetarischen Gemüsepfanne mit Kokosmilch und Basmatireis? Diese Gemüsepfanne ist cremig und würzig zugleich, die Kokosmilch liefert gesunde Fette und der Basmatireis komplexe Kohlenhydrate. Ein leichtes und sättigendes Abendessen für einen erholsamen Schlaf.

Eine weitere köstliche Option für ein gesundes Abendessen ist ein Hühnchencurry mit Kurkuma und Ingwer. Dieses Curry ist entzündungshemmend und verdauungsfördernd, das Hühnchen liefert hochwertiges Eiweiß und die Gewürze sorgen für eine aromatische Note. Ein wärmendes und nahrhaftes Abendessen für einen guten Start in die Nacht.

Das Finden von kreativen und gesunden Rezepten zum Abnehmen kann helfen, den Weg zur Traumfigur zu erleichtern. Probieren Sie die vorgestellten Rezepte aus und lassen Sie sich von ihrer Vielfalt und köstlichen Geschmack überzeugen. Mit einer ausgewogenen und abwechslungsreichen Ernährung ist es möglich, Gewicht zu verlieren und dabei genussvoll zu essen.

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This heartbreaking story will make you question everything about trust, accountability, and friendship. When Sarah's roommate accidentally left her expensive weight loss medication out of the fridge, destroying nearly $600 worth of doses, what started as an honest mistake turned into a nightmare scenario. Without insurance, this medication represented months of sacrifice and her hope for a healthier future. But when her roommate refused to pay for the damage, citing that it wasn't "life-saving like insulin," Sarah faced an impossible choice. Should she take legal action against someone she trusted, or absorb the devastating loss? This story touches on healthcare costs, roommate relationships, personal responsibility, and the difficult decisions we face when accidents have expensive consequences. Watch to see how this situation unfolds and let us know what you would do in the comments! #WeightLossJourney #RoommateProblems #LegalAdvice #HealthcareCosts #PersonalResponsibility #TrustIssues #ExpensiveMistakes #Friendship #Justice #MoralDilemma

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Are you tired of constantly struggling to reach your fitness goals? Do you find yourself feeling overwhelmed by the endless amount of information out there on how to achieve and maintain a healthy lifestyle? Look no further, because Fitastic Keto gummies are here to help you achieve your fitness goals in a delicious and convenient way.

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Don’t let your fitness goals continue to elude you. With Fitastic Keto gummies, you can take control of your health and wellness and achieve the results you’ve always dreamed of.

Summary and FAQ

In summary, Fitastic Keto gummies are a convenient and delicious way to support your fitness goals and improve your overall health. These gummies are packed with essential nutrients and scientifically proven ingredients that can help boost your metabolism, increase energy levels, and enhance weight loss support.

If you have any questions about Fitastic Keto gummies or how they can help you achieve your fitness goals, check out our frequently asked questions below:

1. Are Fitastic Keto gummies safe to use?

Yes! Fitastic Keto gummies are made with natural ingredients and undergo rigorous testing to ensure quality and safety.

2. How quickly will I see results with Fitastic Keto gummies?

Results may vary, but many users report seeing noticeable improvements in energy levels and weight loss support within a few weeks of incorporating these gummies into their routine.

3. Can I take Fitastic Keto gummies if I have dietary restrictions?

Fitastic Keto gummies are gluten-free and GMO-free, making them a safe and healthy option for individuals with dietary restrictions.

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Common fitness advice has led you to believe you can only have one or the other: If you want muscle growth, you have to bulk and put on unnecessary amounts of fat that you’ll eventually have to get rid of to even reveal the muscle you’ve built. If you want fat loss, you have to cut and (possibly) lose muscle in the process whilst restricting yourself in an unsustainable manner just to look good until you decide to bulk again. What if I told you the fix was in 2 biological processes everyone has? Metabolism and Hormones. If you can force your metabolism to shift between tapping into fat stores (catabolism) AND preserving + building muscle (anabolism) Along with dialing in your hormonal profile to effectively signal to your body when you want those anabolic vs. catabolic hormones to actually be present. Whose to say you can’t build muscle and lose fat year-round without having to shift between bulks and cuts? Although it’s simple, it doesn’t mean it’s easy. Hence why I’m introducing the idea and dedicating myself towards experimentation to find a way to create a system that works to achieve this. It certainly is possible, and with enough time and intention + a bit of tinkering revolved around these 2 levers, Your body will have no choice but to turn into a muscle building, fat burning machine. This is the way of 2.0.

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