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(USMLE topics) Methamphetamine: mechanism of action, short-term and long-term effects, addiction and overdose. Purchase a license to download a non-watermarked copy of this video on AlilaMedicalMedia(dot)com ©Alila Medical Media. All rights reserved. Voice by: Ashley Fleming All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. Methamphetamine, also called meth or crystal meth, among other names, is a psychostimulant drug mainly known for its recreational use. Methamphetamine is chemically similar to amphetamine, a drug used to treat attention-deficit hyperactivity disorder, obesity and narcolepsy; but being more potent and highly addictive, methamphetamine is rarely prescribed for medical treatments. Most commonly, the drug is produced illegally, from pseudoephedrine, an ingredient in cold medicines. It can exist as white powder, pills, or bluish-white crystals, and can be consumed by swallowing, smoking, snorting, or injecting. Methamphetamine acts to increase the amount of a neurotransmitter called dopamine in the brain. Dopamine is at the basis of the brain reward pathway, which is designed to “reward” the body for important behaviors that are essential for survival, such as feeding when hungry. Engaging in enjoyable activities causes dopamine release from dopamine-producing neurons into a space between neurons, where it binds to and stimulates its receptors on the neighboring neuron. This stimulation is believed to produce pleasurable feelings or rewarding effect. Normally, dopamine molecules are promptly cleared from the synaptic space to ensure that the postsynaptic neurons are not over-stimulated. This is possible thanks to the action of dopamine-transporter, which channels dopamine back to the transmitting neuron. Methamphetamine binds to dopamine-transporter and blocks dopamine re-uptake. In addition, it can enter the transmitting neuron and trigger more dopamine release. The result is that dopamine builds-up in the synapse to a much greater amount than normal. This produces a continuous over-stimulation of receiving neurons and is responsible for the prolonged and intense euphoria experienced by drug users. At a low dose, methamphetamine stimulates the brain and can elevate mood and alertness; and by accelerating heart rate and breathing rate, it increases energy in fatigued individuals. It also reduces appetite and promotes weight loss. These seemingly “positive” effects keep users coming back for more, eventually leading to addiction and potential overdose. Long-term drug users may experience extreme weight loss, severe dental damage, and constant hyperactivity which results in anxiety, sleeping disorders and violent behaviors. Overdose takes the drug’s effects to the extreme and can cause psychosis, heart attacks, seizures, strokes, organ failures, and even death. Currently, there is no approved pharmacological treatment for methamphetamine addiction; the most effective treatments are cognitive behavioral therapies.
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The subject of weight loss pills has for long been a very controversial issue in the health and wellness industry. There are so many options available on the market, it can be difficult to determine which ones are safe and effective. Nonetheless, when it comes to FDA approved over-the-counter weight loss pills, you can rely on them as they have undergone rigorous testing to ensure efficacy and safety.
We will take a look at some of the best over-the-counter weight loss pills that have been approved by the FDA in this article. These reliable choices can assist you in losing weight safely and sustainably. It is important to consult with your healthcare provider before commencing any new plan for losing weight, just to be sure that these supplements suit your individual requirements.
These FDA-approved weight loss pills help restart your journey or bust through plateaus. And there is a wide range of such options from appetite suppressants to fat burners that will suit one’s particular needs.
For instance, remember that weight loss pills do not work by magic but should be used together with a healthy diet as well as regular physical exercise. Therefore, it is essential to approach shedding off pounds holistically with overall health and well-being being paramount considerations. From this reading piece you will learn about some of the top FDA-approved weigh-loss remedies towards a better way of living.
1.Garcinia Cambogia
Garcinia Cambogia is one common type of weightloss supplement recognized by FDA as an over –the -counter . This naturally derived fruit extract contains hydroxycitric acid (HCA) thought to reduce appetite and block fats production in our bodies.Studies have proven Garcinia Cambogia effective for reducing body mass if used along with a balanced diet and exercises .
It is significant therefore only opt for high-quality Garcinia Cambogia supplements containing not less than 50% HCA free from additives compounds or artificial components . You can always rely on Garcinia Cambogia when taken as directed towards supporting your weight loss objectives and also promoting overall well-being.
However, before you take any new supplement it is important to see your healthcare provider first. Although generally safe for most people, Garcinia Cambogia may interact with certain medications or medical conditions.It is imperative to consult a health care provider to ensure that you are taking the appropriate supplements specifically meant for you.
2.Orlistat (Alli)
Orlistat sold as Alli is an FDA approved drug which prevents fat from being absorbed into the intestines. The over-the-counter version of this medication comes in lower doses compared to its prescription counterpart Xenical and should be taken along with meals so that fats absorbed by the body can be reduced.
Orlistat is best suited for individuals who are overweight or obese and have struggled to lose weight through diet and exercise alone. In combination with a calorie-restricted diet and regular physical activity, Orlistat can promote weight loss and improve overall health outcomes.
Taking this medication correctly is of vital importance including following the instructions for dosing Orlistat and prioritizing healthy eating habits. The absorption of fat being blocked by Orlistat, it may also prevent the body from absorbing necessary nutrients; thus, a balanced diet should be maintained while on this supplement.
3. Green Tea Extract
Green tea extract is a natural product which has been found to have various health benefits such as supporting weight loss. Consequently, it is safe to use green tea extract over the counter (OTC) hence individuals can confidently choose it when they want to boost their weight loss efforts.
Epigallocatechin gallate (EGCG), an antioxidant found in green tea extract, stimulates thermogenesis and promotes fat oxidation. It has been shown that taking green tea extract can help support weight loss if you are combining it with a healthy diet and regular exercise program.
To get the best results from using green tea extract, one must select a well-made product that contains certified amounts of catechins. By adding green tea extracts into your daily life to support your losing pounds objectives and improve general health conditions.
4. Caffeine
Caffeine is frequently included in many OTC weight-loss pills because it stimulates metabolism and promotes excess fat burning. This is why caffeine was approved for OTC use by the FDA making it popular among people who want to speed up their weight-loss process.
Moderate consumption of caffeine increases energy levels, reduces hunger pangs and enhances mental alertness or focus. Scientific researches indicated that caffeine intake may elevate calorie expenditure related to physical activity hence increasing its contribution towards body mass reduction.
Keep track on how much caffeine you consume so as not to exceed recommended intake since this could lead to negative side effects like jitteriness, restlessness and insomnia among others. If taken responsibly during your journey toward weight loss, caffeine will enable you enjoy all these benefits without any harm thereby supporting overall health.
5. Glucomannan
Glucomannan is a natural water-soluble dietary fiber that has been approved by the FDA as an OTC weight-loss supplement. It comes from the roots of the konjac plant and is known for its ability to absorb water, forming a gel-like substance in the stomach that helps promote fullness and reduce appetite.
Glucomannan has been found to slow down stomach emptying leading to increased satiety and hence promotes weight loss. When combined with a healthy diet and regular exercise, glucomannan can also help minimize calories intake thus reducing body mass.
Helps prevent choking or blockages in your throat or intestines by taking glucomannan with at least 8 ounces of water or other liquid. By taking note on how you should use it along with changing your lifestyle, the medicine will assist you achieve what you want concerning your health outcome.
To sum up, there are several OTC weight loss pills which have been approved by FDA to help you reach your weight goal. Hence, their safety and effectiveness can be trusted since these supplements have undergone extensive testing prior to their approval. Furthermore, before starting any new weight loss program ensure that you consult with your healthcare provider who will then emphasize on adopting whole approach towards well-being.
Whether you prefer Garcinia Cambogia, Orlistat, green tea extract, caffeine or glucomannan, each of these weight loss pills has its own unique advantages to aid you on your journey towards a better life. Reaching your weight loss target can be achieved with a good mix of diet, exercise and supplementation.
Remember that losing weight is a marathon race that demands dedication, endurance and perseverance. With FDA-approved weight loss prescription drugs in the picture however, one’s efforts could be boosted for long lasting impacts. Identify what suits your personal needs including supplements and know that it is possible to lose sustainable weight if given the right support and resources.
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The Best Treadmill Workouts For Burning Fat | Lusha Health Point In order to burn fat, you'll want to focus on the basics. Consistently strength training, eating at a calorie deficit, and regular aerobic activity are all key players here. And one of the best machines you can use for anaerobic span work is a treadmill. In addition to the fact that, not onlyit forces you to work at a reliable speed, however at whatever point the climate conditions outside are whether excessively cold or hot, down-pouring, or snowing, you can count on your trusty treadmill to still get a solid workout in. If you're not sure where to begin, here are four treadmill workouts that can help you to burn fat. But before performing any of these workouts, make sure to do a proper warmup for injury prevention and also to get your body primed for the session. Then, choose one of the following cardio workouts to include in your routine. ================================== #lushahealthpoiint #best #fat #new #video
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Today’s article is a comprehensive review on Optimal Keto ACV Gummies. These gummies have been gaining popularity for promising and effective benefits in recent years. If you have been taking keto supplements to improve your health and fitness, these gummies are a must-have anytime. In this review, we delve into this supplement’s health benefits, its science-backed formulation, and much more about these gummies.
The Science Behind Optimal Keto ACV Gummies
With its natural ingredients that come straight from Mother Nature, Optimal Keto ACV Gummies help you get in ketosis so you can accelerate weight loss and curb hunger. Made with organic apple cider vinegar (ACV), a fermented food recognized for a wealth of health benefits, those with ACV in their diet and lifestyle have experienced weight loss, improvements in digestion, and reduced blood sugar. It also suppresses appetite and cravings. When consumed repeatedly, the body is able to reach its optimal fat-burning state and achieve sustainable weight loss benefits. As an excellent supplement to burn fat, keto plays a key role in this weight loss plan.
One ingredient in Optimal Keto ACV Gummies is beta-hydroxybutyrate (BHB), a ketone body made by the liver when fasting or on a very low-carb diet like keto, which can increase your energy, mental clarity, and ease cravings so that you stick to the keto lifestyle.
Also, these gummies help you extract optimum nutrients from keto fruits that can strengthen your body, enhance immunity and inculcate sound health. In simple words, you can support your ketogenic diet radically with Optimal Keto ACV Gummies and achieve your ultimate well-being and fitness goals with ease.
Benefits of Optimal Keto ACV Gummies
There are numerous benefits of taking Optimal Keto ACV Gummies. The reason why people are drawn to the ketogenic lifestyle is to live healthy. Our gummies help them combat headaches, fatigue and cravings that occur throughout the journey, as well as support their bodies in transitioning into ketosis more quickly.
Also Optimal Keto ACV Gummies could boost your energy level to help have enough energy to continue while following keto diet. Stable energy level helps you focus and keep on working consistently without any crashes. It boosts your energy level so much that you don’t feel sleepy during day time.
Secondly, as we discussed before, these gummies help digestion, which improves nutrient absorption to make the most of the foods you eat, reducing appetite to prevent overeating and snacking on junk foods.
How to Incorporate Optimal Keto ACV Gummies Into Your Routine
Take Optimal Keto ACV Gummies for 30-60 days along with a proper diet and physical activity for better and long-term results. The most recommended intake is 2 gummies per day with a glass of regular water, in the morning and in the evening, either before or after having food.Drinking a glass of regular water throughout the day is a must so that the detoxification process runs smoothly and effectively.
In order to achieve your desired results with Optimal Keto ACV Gummies, it is recommended that you follow a balanced keto diet which is high in healthy fats and proteins and low in carbs. Make sure to eat lots of leafy greens, non-starchy vegetables and quality meats, though.
In addition, make sure you stay active and ease into your workouts with Optimal Keto ACV Gummies to reap the most from them. Whether it’s yoga, cardio, rock climbing or weight lifting, finding and engaging in the physical activity of your choice that you love can boost your keto fitness goals, help you feel better and see results even faster.
Frequently Asked Questions About Optimal Keto ACV Gummies
Is it true that Optimal Keto ACV Gummies take too long to work? How long should you wait for these gummies to work?
It varies from person to person, but most report that the gummies make them more energetic, attentive and satiated in the period of a few days; after several weeks use, it’s said to become even more positive. They also report weight loss and improved digestion.
2. Are there any side effects associated with Optimal Keto ACV Gummies?
For most people, Optimal Keto ACV Gummies are harmless enough for them to take, although a handful of folks might experience a few mild side effects like gastrointestinal discomfort or perhaps certain allergies. You should always consult your healthcare provider in case you have any questions or worries about taking Optimal Keto ACV Gummies. Are you prepared to begin?
3. Can I consume these dietary supplements Optimal Keto ACV Gummies benefits if I am not following a ketogenic diet?
Still, you can take Optimal Keto ACV Gummies even without adhering to a strict ketogenic diet because the health-promoting ingredients of these gummies can aid weight loss, digestive health, energy levels, cognition, and other essential aspects of health and wellnes.
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MY FAT LOSS PLAN http://www.leansecrets.com TWITTER http://www.twitter.com/leansecrets FACEBOOK http://www.facebook.com/LeanSecrets ---------------------------------------------------------------------------------------------------------- The information in this video is designed for educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health problems or illnesses without consulting your doctor. Please consult a doctor with any questions or concerns you might have regarding medical conditions, or before starting any fitness or diet regimen
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