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💊 Are GLP-1 Drugs Beneficial or Challenging? Let’s Uncover the Truth! 💊 GLP-1 medications like Ozempic, Wegovy, Zepbound, and Mounjaro have gained massive attention for weight loss and diabetes management—but are they truly beneficial, or do they come with hidden challenges? 🤔 In this episode of Healthy by George, we break down: ✅ How GLP-1 drugs work in the body 🧬 ✅ The benefits for weight loss and blood sugar control 🏥 ✅ Potential side effects and long-term concerns ⚠️ ✅ Who should (and shouldn’t) consider using them ❓ While these medications have transformed many lives, there’s more to the story than just weight loss. Understanding the pros and cons is key to making informed health decisions! 💡 💬 Have you or someone you know used GLP-1 drugs? Share your experiences in the comments! Don’t forget to like, subscribe, and share to help others stay informed. A journal article was recently published looking at all the available weight loss drugs—mounjaro, wegovy, zepbound, and Ozempic—and new triple G inhibitors being researched. What are we learning? MC shares that these drugs not only help with weight loss, but we are learning they are helpful in other chronic conditions: Substance use disorders Suicidal ideation and schizophrenia Alzheimer's disease and dementia Clotting disorders and infections Chronic obstructive pulmonary disease and liver diseases Chronic obstructive sleep apnea Clearly, these medications are working on a brain-gut association that appears to help in ways that can help reduce individuals from progressing and deteriorating? The question is, why are the drug companies making access to these drugs a challenge by charging such high prices? Plus, physicians and patients are becoming creative with "off-label" use by microdosing. MC shares that she didn't follow the typical aggressive dosing that the research studies did; she stayed on a low dose until she was no longer losing weight on the current dose. MC was on the lowest dose of mounjaro for almost 6 months, losing a small amount each month until it plateaued. This has been MCs approach for each dose of the drug. To stay on that dose until she is no longer getting any benefit. MC believes this has helped her stay on the drug despite some side effects and work with her doctor on the side effects so that they became less and less as time progressed. Now, individuals and physicians use microdosing with GLP1 drugs available from compound pharmacies. Some individuals report many benefits unrelated to obesity but to menopause and its symptoms, but let's do this with the help of our medical professionals. Danger can be possible due to the inability to maintain sterilization when we are reusing drugs in a vial multiple times. Each time we stick the needle into the vial, there is a potential for contamination. Plus, we don't know the long-term problems that could be present from taking microdoses because research has not been done. No matter what your choice is, now is the time to investigate the various ways to help yourself with obesity and other chronic conditions and those reputable online companies or your local doctor to make choices for your health when it comes to using these drugs. MC checks in monthly with her coach and then every quarter with a nutritionist. She also plans to perform a scan to determine her fat-to-muscle ratio and a test to help her understand her metabolism. Be well, my friends. We have this one precious life; let's live it intentionally. 🌿💚 📌 Disclaimer: The views shared here are solely for education and entertainment. They are not endorsed by my employer or any affiliated companies. This content reflects personal perspectives, and I encourage everyone to consult with healthcare professionals for medical advice. Follow us on Social Media: Youtube : https://www.youtube.com/@healthybygeorge3425/videos 🔥INSTAGRAM: https://www.instagram.com/healthybygeorge6/ 💎WEBSITE: https://www.marycatherinegeorge.com/ 🔮FACEBOOK: https://www.facebook.com/profile.php?id=100071895693054 📧 For Business Inquiries 📧 Mail: [email protected] ⚠️ hashtags⚠️ #glp1 #ozempic #wegovy #mounjaro #weightlossdrugs #diabetesmanagement #bloodsugarcontrol #healthybygeorge #weightlossjourney #healthyliving #metabolichealth #obesitytreatment #medicalbreakthrough #glp1sideeffects #insulinresistance #wellnessjourney #guthealth #fitnessandhealth #hormonalbalance #weightlosstransformation #diabetesawareness #hearthealth #lifestylemedicine #nutritionmatters #sciencebasedhealth #stayhealthy #informeddecisions #medicationsafety #holistichealth #preventdisease #healthiswealth

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Here are the top 4 medicines that are not GLP-1's and their weight loss effectiveness. If some of the GLP-1 medications are not covered by insurance or are too expensive, check with your Sequence Clinician to see if Metformin or Bupropion/Naltrexone are right for you.

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Over the years, the ketogenic diet has gained popularity for its ability to help people lose weight and improve their overall health. One product that has recently caught the attention of many is Keto Burning Tablets, which claims to help individuals achieve ketosis faster and burn fat more effectively. Featured on the hit TV show Shark Tank, these tablets have sparked curiosity and skepticism among consumers. In this article, we will explore the effectiveness of Keto Burning Tablets and whether they live up to the hype.

The Science Behind Keto Burning Tablets

Keto Burning Tablets are designed to help individuals following a ketogenic diet reach a state of ketosis faster. Ketosis is a metabolic state in which the body burns fat for energy instead of carbohydrates. By reducing carbohydrate intake and increasing the consumption of healthy fats, the body switches from using glucose as its primary fuel source to burning stored fat. This process can lead to weight loss and other health benefits.

Many people struggle to achieve ketosis on their own, as it can take several days to weeks of strict dieting to reach this state. Keto Burning Tablets claim to expedite this process by providing the body with exogenous ketones, which can help jumpstart ketosis. These exogenous ketones can mimic the effects of natural ketones produced by the body, making it easier for individuals to enter and maintain ketosis.

Potential Benefits of Keto Burning Tablets

There are several potential benefits associated with taking Keto Burning Tablets, including accelerated weight loss, increased energy levels, and improved mental clarity. By helping the body enter ketosis faster, these tablets may aid in burning stored fat more efficiently, leading to quicker weight loss results. Additionally, some users report feeling more energized and focused while taking Keto Burning Tablets, as the brain can function more efficiently on ketones than on glucose.

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While Keto Burning Tablets offer a range of potential benefits, it is essential to be aware of any potential risks or side effects associated with their use. Some individuals may experience digestive issues such as bloating, constipation, or diarrhea when first starting on exogenous ketones. This can be due to the body adjusting to the increase in fat intake or the ingredients used in the tablets.

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Final Thoughts on Keto Burning Tablets

Overall, Keto Burning Tablets may be a useful tool for individuals looking to enhance their ketogenic diet and accelerate their weight loss journey. While they are not a magic solution and should be used in conjunction with a healthy diet and regular exercise, these tablets can provide added support in achieving ketosis and burning fat. As with any supplement, it is essential to do your research, read reviews, and consult with a healthcare provider before making a decision to try Keto Burning Tablets.

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Understanding GLP-1 and Its Role in Weight Management

In recent years, the conversation surrounding weight management and obesity treatment has taken a significant turn, particularly with the advent of GLP-1 receptor agonists. These medications, traditionally used for managing type 2 diabetes, have garnered attention for their secondary effects, including weight loss. GLP-1, or Glucagon-Like Peptide-1, is a hormone that plays a crucial role in glucose metabolism and appetite regulation. In essence, GLP-1 influences the areas of the brain that regulate hunger and satiety, thereby contributing to reduced appetite and increased feelings of fullness after eating.

The rise in obesity rates globally has prompted researchers and healthcare professionals to explore therapeutic options that extend beyond conventional lifestyle changes. Among these options, GLP-1 agonists have emerged as a promising solution, leading to not only weight loss but also associated improvements in metabolic health. The idea that a medication can aid in weight management opens up new avenues for those struggling with obesity, offering hope for a more effective alignment of treatments that address both physical and psychological aspects of eating disorders.

As of 2025, research and clinical trials have led to the development of oral formulations of GLP-1 medications, making them more accessible and easier to use compared to their injectable counterparts. This transformation in the delivery method has implications for patient adherence and overall treatment success. In this article, we will compare three of the leading oral GLP-1 medications for weight loss, focusing on their mechanisms, efficacy, potential side effects, and overall patient experience. By demystifying these medications, we aim to provide insights into how they can fit into a comprehensive strategy for weight management.

GLP-1 Oral Medication 1: Semaglutide (Brand Name: Wegovy)

Semaglutide, marketed under the brand name Wegovy, is one of the most recognized GLP-1 receptor agonists in the weight loss landscape. Initially approved for diabetes management, its efficacy in promoting weight loss was established through large-scale clinical trials. Semaglutide works by mimicking the effects of GLP-1, enhancing glucose-dependent insulin secretion, and significantly reducing appetite. Patients taking Semaglutide often report a reduced craving for high-calorie foods and an increased feeling of fullness after consuming meals. This dual action not only aids in weight loss but can also lead to improved metabolic markers, including lowered blood sugar levels and decreased visceral fat.

<p Clinical trials have shown that patients using Semaglutide can achieve substantial weight loss, with some participants losing an average of 15% of their body weight over a year. This level of weight reduction is significant enough to have potential health benefits, such as lowering the risk of cardiovascular diseases and improving overall quality of life. However, it is important to note that Semaglutide is typically prescribed alongside a calorie-controlled diet and increased physical activity, ensuring a holistic approach to weight management.

While the advantages of Semaglutide are notable, potential side effects should be considered. Common side effects may include gastrointestinal issues such as nausea, vomiting, and diarrhea. Although these symptoms often subside after the initial weeks of treatment, some patients may find them difficult to tolerate. It is crucial for individuals considering Semaglutide to engage in an open discussion with their healthcare provider regarding their health history and any medications they currently take, as this can help mitigate adverse reactions and ensure a safer, personalized treatment plan.

GLP-1 Oral Medication 2: Tirzepatide (Brand Name: Mounjaro)

Tirzepatide, sold under the brand name Mounjaro, represents a breakthrough in the realm of GLP-1 medications as it targets not just the GLP-1 receptors but also various metabolic pathways associated with appetite regulation. This dual-target mechanism allows for a more robust effect on weight loss and improves glycemic control, making Tirzepatide a versatile option for individuals struggling with obesity and type 2 diabetes. The clinical trials for Tirzepatide have indicated that patients can achieve weight loss percentages even higher than those seen with Semaglutide, showcasing its enhanced efficacy in fat reduction.

What sets Tirzepatide apart is its ability to promote substantial weight loss outcomes while simultaneously helping manage blood glucose levels. In clinical studies, those treated with Tirzepatide have reported an average weight loss of around 15 to 20% of body weight after a year of treatment, making it an attractive option for individuals looking for effective ways to manage their weight. Enhanced feelings of satiety, even when consuming regular meal portions, are part of the benefits reported by patients, easing the burden of constantly feeling deprived or hungry.

Regarding side effects, Tirzepatide’s profile includes common adverse reactions similar to other GLP-1 medications, like gastrointestinal disturbances. However, due to its dual-action mechanism, it might also come with a distinct set of effects that need further research. This highlights the importance of individualized medical assessments before starting Tirzepatide. Overall, Tirzepatide stands out for its strong efficacy in both weight management and metabolic control, making it a vital part of the conversation around GLP-1 medications.

GLP-1 Oral Medication 3: Liraglutide (Brand Name: Saxenda)

Liraglutide, known by the brand name Saxenda, has long been part of the treatment options available for obesity management. Initially approved for diabetic patients, Saxenda became available for weight management based on its gratifying results in clinical trials. Like other GLP-1 medications, Liraglutide works to increase satiety and slow gastric emptying, thereby controlling appetite and helping with food intake. The unique aspect of Liraglutide is that it is delivered through injection; however, it is also essential to include it in the oral GLP-1 discussion, as many patients look for alternatives to injections.

In terms of weight loss efficacy, Liraglutide has shown positive outcomes, with studies demonstrating that participants can lose up to 10–15% of their body weight over several months of treatment. Besides weight reduction, it also contributes to health improvements such as decreased risk factors for diabetes and heart-related issues. For individuals struggling with obesity, the option to use Liraglutide can encourage engagement with healthier lifestyle choices while benefiting from ongoing medical support. A healthcare provider’s guidance is paramount for anyone considering Liraglutide.

Despite its advantages, it is crucial to understand the potential side effects associated with Liraglutide. As with other GLP-1 medications, patients may experience gastrointestinal symptoms such as nausea, vomiting, and constipation. Understanding these side effects can help prepare patients better, allowing them to manage side effects effectively should they arise. This preparation ultimately aids in maintaining the treatment regimen and achieving successful weight loss outcomes. Thus, Liraglutide remains a considerable contender within the GLP-1 medication spectrum.

Effectiveness of GLP-1 Medications in Weight Loss: A Comparative Analysis

When evaluating the effectiveness of the three GLP-1 medications—Semaglutide, Tirzepatide, and Liraglutide—it’s essential to consider both clinical outcomes and individual patient experiences. While each medication operates on the same fundamental principle of enhancing GLP-1 signaling, their varying mechanisms and formulations lead to differences in effectiveness, patient adherence, and overall satisfaction. Semaglutide has shown impressive weight loss results, often regarded as the gold standard in GLP-1 therapy. Its approval for both diabetes and weight loss solidifies its reputation, and many healthcare providers advocate its use due to favorable outcomes.

On the other hand, Tirzepatide’s dual-action mechanism provides a compelling alternative for those who may not have experienced satisfactory results with Semaglutide. The additional metabolic pathways it addresses can prove beneficial for a more diverse group of individuals, especially those with complex metabolic concerns and obesity-related comorbidities. With significant treatment outcomes reported, Tirzepatide’s place within weight management strategies is being increasingly recognized.

Liraglutide, despite being used longer, might not yield the same extent of weight loss in comparison to newer medications. However, its established presence in the market and familiarity among patients and healthcare professionals contribute to its continued use. Patients’ preferences play a crucial role in medication selection, with factors such as ease of administration, potential side effects, and personal health goals greatly influencing which GLP-1 therapy is chosen. Understanding the nuances of these GLP-1 medications can empower individuals to make informed decisions regarding their treatment options.

Common Questions About GLP-1 Medications and Weight Loss

As GLP-1 medications gain traction in the realm of weight management, many individuals are left with questions regarding their use, safety, and overall effectiveness. A common query is whether these medications are suitable for everyone struggling with obesity. While GLP-1 medications have proven effective for many individuals, they may not be appropriate for everyone. It is crucial for individuals to consult with healthcare professionals who can assess their personal and medical history and recommend the best course of treatment. A comprehensive evaluation that includes assessing potential contraindications ensures that patients receive safe and effective care.

Another frequently asked question pertains to the duration of treatment. Many individuals wonder if GLP-1 medications are intended for long-term use or if they are designed for short-term weight loss. In reality, the efficacy of these medications is often seen with ongoing use; hence discontinuation can lead to weight regain. Patients are encouraged to view these medications as part of a broader lifestyle change rather than a quick fix. Ongoing support from healthcare professionals, coupled with behavioral changes in diet and exercise, enhances the likelihood of maintaining weight loss long-term.

Lastly, the question of side effects is a primary concern for many prospective users of GLP-1 medications. While most individuals tolerate these medications well, gastrointestinal symptoms are commonly reported. Users should understand that side effects can vary based on personal health factors and the specific medication chosen. It is essential for anyone considering GLP-1 therapy to engage in thorough discussions with healthcare providers regarding expectations, potential experiences, and ways to minimize adverse reactions. By addressing these common questions, individuals can better navigate their weight loss journey, harnessing the benefits of GLP-1 medications effectively.

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Xenical (Orlistat)

Xenical, also known by its generic name Orlistat, is a prescription weight loss medication that works by blocking the absorption of fat in the intestines. It is approved for use in adults with a BMI of 30 or above, or 27 or above with obesity-related health conditions. Xenical is typically taken with meals to prevent the absorption of dietary fat and can help users lose an average of 5-10% of their body weight.

Like all medications, Xenical comes with potential side effects, including oily stools, gas, and bloating. It is important to follow a low-fat diet while taking Xenical to minimize these side effects. Additionally, Xenical may interfere with the absorption of certain vitamins and minerals, so it is recommended to take a multivitamin supplement while using this medication.

Xenical may not be suitable for everyone, including pregnant or breastfeeding women, individuals with certain gastrointestinal conditions, and those taking certain medications. It is important to consult with a healthcare provider before starting Xenical to ensure it is a safe and appropriate option for you.

Contrave

Contrave is a combination weight loss medication that contains bupropion and naltrexone. It is approved for use in adults with a BMI of 30 or above, or 27 or above with obesity-related health conditions. Contrave works by reducing appetite and cravings while increasing metabolism, leading to weight loss.

Common side effects of Contrave include nausea, constipation, headache, and insomnia. Some users may also experience an increase in blood pressure or heart rate while taking this medication. It is important to monitor these side effects and consult with a healthcare provider if they become bothersome or severe.

Contrave may not be suitable for individuals with certain medical conditions, including eating disorders, uncontrolled hypertension, or a history of seizures. It is important to inform your healthcare provider of your complete medical history before starting Contrave to ensure its safety and effectiveness for you.

Qsymia

Qsymia is a prescription weight loss medication that contains a combination of phentermine and topiramate. It is approved for use in adults with a BMI of 30 or above, or 27 or above with obesity-related health conditions. Qsymia works by suppressing appetite and increasing feelings of fullness, leading to reduced food intake and weight loss.

Common side effects of Qsymia include dry mouth, constipation, insomnia, and dizziness. Some users may also experience mood changes or cognitive impairment while taking this medication. It is important to monitor these side effects and consult with a healthcare provider if they become concerning.

Qsymia may not be suitable for individuals with certain medical conditions, including glaucoma, hyperthyroidism, or a history of kidney stones. It is important to discuss your medical history with your healthcare provider before starting Qsymia to ensure its safety and effectiveness for you.

Saxenda

Saxenda is a prescription weight loss medication that contains liraglutide. It is approved for use in adults with a BMI of 30 or above, or 27 or above with obesity-related health conditions. Saxenda works by mimicking a hormone that regulates appetite and food intake, leading to reduced caloric intake and weight loss.

Common side effects of Saxenda include nausea, diarrhea, constipation, and headache. Some users may also experience low blood sugar levels while taking this medication. It is important to monitor these side effects and consult with a healthcare provider if they become problematic.

Saxenda may not be suitable for individuals with certain medical conditions, including a history of pancreatitis or thyroid cancer. It is important to disclose your medical history to your healthcare provider before starting Saxenda to ensure its safety and effectiveness for you.

Alli (Orlistat)

Alli, the over-the-counter version of Xenical, is an FDA-approved weight loss pill that works by blocking the absorption of fat in the intestines. It is approved for use in adults with a BMI of 25 or above and can help users lose an average of 5-10% of their body weight. Alli is typically taken with meals to prevent the absorption of dietary fat and is recommended for those looking to lose a moderate amount of weight.

Like Xenical, Alli comes with potential side effects, including oily stools, gas, and bloating. It is crucial to follow a low-fat diet while taking Alli to minimize these side effects. Additionally, Alli may interfere with the absorption of certain vitamins and minerals, so it is recommended to take a multivitamin supplement while using this medication.

Alli may not be suitable for everyone, including pregnant or breastfeeding women, individuals with certain gastrointestinal conditions, and those taking certain medications. It is important to consult with a healthcare provider before starting Alli to ensure it is a safe and appropriate option for you.

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Summary

Overall, FDA-approved weight loss pills can be a helpful tool for those looking to lose weight and improve their health. However, it is essential to remember that these pills are not magic bullets and should be used in conjunction with a healthy diet and regular exercise. Consulting with a healthcare provider is crucial to determine which weight loss pill is right for you based on your individual needs and medical history.

Before starting any weight loss medication, it is important to understand the potential side effects and risks associated with them. Monitoring your progress and discussing any concerns with your healthcare provider can help ensure a safe and effective weight loss journey. With the right guidance and support, FDA-approved weight loss pills can be a valuable tool in achieving your weight loss goals.

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One and done. Kendra Wilkinson revealed she recently started taking a weight loss medication — but decided to stop after just one dose. The former Playboy model, 39, told her Instagram followers Wednesday that she “started the weight loss shots” but quickly changed her mind. “Only did one. Nevermind [sic]. Throwing away!!” she wrote on her Stories. In a follow-up post, Wilkinson explained that the potential negative side effects drastically outweighed the benefits. “A lot of you ask why i threw away the shots. I’m actually ok with a little weight gain,” she wrote atop a selfie. “Happier in life now a days [sic].” The mother of two — who shares son Hank IV, 15, and daughter Alijah, 10, with ex-husband Hank Baskett — said she has “heard too many horror stories” about people suffering medical complications as a result of the medications. “People end up in ER. Surgeries. No thanks,” she added. It is unclear which diabetes-turned-weight loss drug — such as Wegovy, Mounjaro and Ozempic — Wilkinson used. While several GLP-1 drugs are FDA-approved, they can cause gastrointestinal issues or more serious, but rare, issues like low blood pressure, pancreatitis or kidney problems, per the Cleveland Clinic. The real estate agent began taking the weight loss drug after facing backlash about her body from social media trolls. In January, she clapped back at body-shaming haters after they commented on her curvy physique. “Yes, I’ve gained weight. Yes, im aging. Yes, I’m not that girl i was before (playboy girl) 🤣,” she captioned a mirror selfie. Despite the changes, Wilkinson said she is finally feeling “good and mentally healthy” for the first time in a while, noting that her life is “pretty balanced” and she is “working out and cooking a lot more.” “For those of you hating on my new weight [and] 40 yr old face please know that I’m happy, healthy and at peace in life finally,” she continued. “Leave me alone and respect that I’m where I actually want to be finally all together.” While the former model is “feeling amazing,” she jokingly admitted she does need to work on her “alcohol intake.” “I hear you and that will be monitored better. Drinking too much is definitely drinking too much but you know what’s coming up in JUNE…. Shots. 😂,” she wrote, an apparent hint at her short-lived decision to take weight loss medication. Although Wilkinson went back on her decision to try one of the semaglutide variations, she still found other ways to stay fit, such as pole dancing classes, tennis and weight lifting. However, she admitted last month that she has a hard time sharing on social media due to the mean comments. “God, it takes me a second to post photos now. Wondering how much hate and bullying I’ll get for my new body and age but I’m going to post this today and feel proud of myself,” she wrote on Instagram. “I have overcome so much in life and deserve to celebrate myself and my new attitude towards life. “If people don’t like me or this or think I’m bigger or i can’t turn men on anymore GOOD then there’s the door.” . . . . . *** Fair Use Disclaimer: - This video is transformative and does not harm or compete with the original works. - All content is created for educational or informational purposes. - Only limited visual and audio materials are used, strictly when necessary. - The purpose of this content is to spread knowledge and raise awareness. Note: This disclaimer is intended to support compliance with content policies and provide context for the material shared.

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